Green I, Behar A J, Shanon E, Gorsky M
Department of Otorhinolaryngology, Ichilov Hospital, Tel Aviv Israel Medical Center, Sackler School of Medicine, Tel Aviv University.
Arch Otolaryngol Head Neck Surg. 1988 May;114(5):561-3. doi: 10.1001/archotol.1988.01860170091026.
Multifocal eosinophilic granuloma (Hand-Schüller-Christian disease) confined to soft tissues in the head and neck region is described in a man, 32 years of age. The lesions were detected at varying time intervals within a period of 14 months. They were located in the gingivae, the submaxillary salivary glands, the thyroid gland, and in the dermal lining of the external auditory meatus. Clinical, histologic, ultrastructural, and immunohistochemical findings are presented and discussed. Some of these findings go along with the tenet that the typical proliferating histiocyte in eosinophilic granuloma is a pathologic Langerhans' cell, or a close kindred to it.
本文描述了一名32岁男性，其头颈部软组织出现多灶性嗜酸性肉芽肿（汉-许-克病）。这些病变在14个月内的不同时间间隔被发现。它们位于牙龈、颌下唾液腺、甲状腺以及外耳道的皮肤内衬。文中展示并讨论了临床、组织学、超微结构和免疫组化的研究结果。其中一些结果支持了这样的观点，即嗜酸性肉芽肿中典型的增殖性组织细胞是病理性朗格汉斯细胞，或者是与之密切相关的细胞。
