Schulman J A, Leveque C, Coats M, Lawrence L, Barber J C
Department of Ophthalmology, University of Texas Medical Branch, Galveston 77550.
Br J Ophthalmol. 1988 Mar;72(3):171-5. doi: 10.1136/bjo.72.3.171.
A 33-year-old man was treated with systemic steroids for a retinal inflammatory lesion before the diagnosis of cryptococcal retinitis and meningitis was suspected. He died from central nervous system disease despite treatment with parenteral antifungals. Histopathological studies demonstrated ocular and disseminated systemic infection with Cryptococcus neoformans. Direct cryptococcal involvement of the eye is rare and is usually associated with disseminated disease. Systemic steroids must be used with caution, and patients who take these drugs require frequent monitoring.
一名33岁男性在被怀疑患有隐球菌性视网膜炎和脑膜炎之前，因视网膜炎性病变接受了全身性类固醇治疗。尽管接受了胃肠外抗真菌药物治疗，但他仍死于中枢神经系统疾病。组织病理学研究显示眼部和全身存在新型隐球菌感染。隐球菌直接累及眼部较为罕见，通常与播散性疾病相关。全身性类固醇必须谨慎使用，服用这些药物的患者需要频繁监测。
