2nd Orthopedic and Traumatologic Clinic, University of Pisa, Pisa, Italy .
2nd Orthopedic and Traumatologic Clinic, University of Pisa, Pisa, Italy.
Acta Biomed. 2020 Dec 30;91(14-S):e2020005. doi: 10.23750/abm.v91i14-S.10785.
Osteosarcopenia is a new concept of association of osteoporosis and sarcopenia. Both of these pathologies are more frequent in old people and general affects all the skeleton with increased risk of falls and fractures, loss of global function, fragility, and mortality, but also surgical failures. The coexistence of these condition derives from a close relationship, not only anatomical, between bone and muscle tissues. Sometimes these pathological conditions can involve only a skeleton segment, due to local disuse, causing a district form of sarcopenia. In this clinical case, Authors describes a case of isolated lower limb osteosarcopenia in a young non-osteoporotic patient, due to a prolonged limb disuse, complicated by surgical treatment failure for previous pathology, diagnosed by clinical, laboratory, instrumental and histopathological exams.
骨质减少症是骨质疏松症和肌肉减少症合并的新概念。这两种病理在老年人中更为常见，普遍影响全身骨骼，增加跌倒和骨折的风险、降低整体功能、导致脆弱性和死亡率增加，还会导致手术失败。这些情况的共存源于骨骼和肌肉组织之间的密切关系，不仅是解剖上的关系。有时这些病理情况可能只涉及单个骨骼节段，由于局部废用导致局部形式的肌肉减少症。在这个临床病例中，作者描述了一例年轻非骨质疏松患者因肢体长期废用导致的孤立性下肢骨质减少症，之前的病理导致手术治疗失败，通过临床、实验室、仪器和组织病理学检查进行诊断。
