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胆囊切除术后胆道损伤:频率,以及早期与晚期内镜逆行胰胆管造影的作用。

Postcholecystectomy biliary injuries: frequency, and role of early versus late endoscopic retrograde cholangiopancreatography.

机构信息

Hepatology, Gastroenterology and Infectious Diseases Department.

Surgery Department, Kafrelsheikh University, Kafrelsheikh.

出版信息

Eur J Gastroenterol Hepatol. 2021 May 1;33(5):662-669. doi: 10.1097/MEG.0000000000002086.

Abstract

BACKGROUND AND STUDY AIM

Bile duct injuries are not infrequently seen during hepatobiliary surgery, particularly after liver transplantation and cholecystectomy. The current study aims to figure out the frequency of postcholecystectomy biliary injuries (PCBI) and the role of early versus late endoscopic retrograde cholangiopancreatography (ERCP) in their management.

PATIENTS AND METHODS

Totally 960 cases operated by both laparoscopic and open cholecystectomy were evaluated in the current study. In total, 942 cases were operated in our institutes, by both laparoscopic (n = 925) and open (n = 17) cholecystectomy, and the frequency of PCBI among patients operated in our institutes was (9/942) 0.95%. Additional 18 cases of PCBI referred to our centers were included in the study. One patient was treated by repair during the surgery, in the remaining 26 patients, ERCP management was attempted. The full details of the 26 patients regarding ERCP management were discussed.

RESULTS

The overall success rate of ERCP management was 88.46% (23/26), whereas 11.54% of cases were treated surgically by choledochal-jejunal anastomosis due to complete common bile duct ligation. There were no differences between patients treated by early (first week) versus late (after the first week) ERCP regarding the needed interventions, type of PCBI, type and diameter of the inserted stents, and the overall success. There were no adverse events associated with ERCP management.

CONCLUSIONS

ERCP was valuable in the treatment of 88.46% of injured cases. There were no differences between early and late ERCP in the treatment of PCBI. Furthermore, ERCP management was not associated with adverse events.

摘要

背景与研究目的

胆管损伤在肝胆外科手术中并不少见,尤其是在肝移植和胆囊切除术后。本研究旨在探讨胆囊切除术后胆管损伤(PCBI)的发生率,以及早期和晚期内镜逆行胰胆管造影(ERCP)在其治疗中的作用。

患者与方法

本研究共评估了 960 例接受腹腔镜和开腹胆囊切除术的患者。共有 942 例在我们的机构接受了手术,包括腹腔镜(n=925)和开腹(n=17)胆囊切除术,在我们机构接受手术的患者中,PCBI 的发生率为(9/942)0.95%。另外,还纳入了 18 例转诊至我们中心的 PCBI 患者。1 例患者在手术中进行了修复,其余 26 例患者尝试进行了 ERCP 治疗。对这 26 例患者的 ERCP 管理的详细情况进行了讨论。

结果

ERCP 治疗的总体成功率为 88.46%(23/26),但由于胆总管完全结扎,11.54%的病例需要进行胆肠吻合术。早期(第一周)和晚期(第一周后)ERCP 治疗的患者在所需干预、PCBI 类型、插入支架的类型和直径以及总体成功率方面均无差异。ERCP 管理无不良事件发生。

结论

ERCP 对 88.46%的损伤病例有治疗价值。早期和晚期 ERCP 在治疗 PCBI 方面无差异。此外,ERCP 管理与不良事件无关。

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