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经内镜逆行胰胆管造影术(ERCP)检测的腹腔镜胆囊切除术后胆系并发症发生率:一家大型三级转诊中心的经验

Frequency of biliary complications after laparoscopic cholecystectomy detected by ERCP: experience at a large tertiary referral center.

作者信息

Khan Mubashir H, Howard Thomas J, Fogel Evan L, Sherman Stuart, McHenry Lee, Watkins James L, Canal David F, Lehman Glen A

机构信息

Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.

出版信息

Gastrointest Endosc. 2007 Feb;65(2):247-52. doi: 10.1016/j.gie.2005.12.037.

Abstract

BACKGROUND

Laparoscopic cholecystectomy has a higher incidence of bile-duct injuries than open cholecystectomy. Although a learning curve phenomenon was attributed to biliary injuries early after its introduction, we were interested in trends in biliary injury rates over time as laparoscopic cholecystectomy has become a mature technology.

OBJECTIVE

To analyze the frequency and anatomic distribution of bile-duct injuries referred after laparoscopic cholecystectomy over a 10-year period.

DESIGN

Retrospective, case-series.

SETTING

Tertiary, referral hepatobiliary unit.

PATIENTS

Referrals to ERCP unit for diagnosis and treatment of biliary injuries after laparoscopic cholecystectomy.

INTERVENTION

ERCP to diagnose level and severity of bile duct injury.

MAIN OUTCOME MEASUREMENTS

Type and anatomy of bile-duct injury, reason for cholecystectomy, mean time between injury and diagnosis, presenting symptoms, ratio of bile-duct injuries diagnosed over total ERCPs done per year.

RESULTS

There were 87 bile-duct leaks, 28 leaks with stones, 51 strictures, and 17 complete duct transactions. The bile-duct injury rate calculated per 100 ERCPs per year was 0.84 (1994), 0.99 (1995), 1.36 (1996), 1.41 (1997), 1.03 (1998), 1.31 (1999), 0.84 (2000), 0.75 (2001), 1.15 (2002), and 0.94 (2003).

LIMITATIONS

Single institution, retrospective analysis, unknown denominator of cholecystectomies done in referral area per year to calculate true bile-duct injury rate.

CONCLUSIONS

Static incidence in frequency, anatomic distribution, and rate per 100 ERCPs per year of postcholecystectomy bile-duct injuries at a tertiary referral hepatobiliary unit over a 10-year period of observation.

摘要

背景

与开腹胆囊切除术相比,腹腔镜胆囊切除术导致胆管损伤的发生率更高。尽管在腹腔镜胆囊切除术引入早期,胆管损伤被归因于学习曲线现象,但随着腹腔镜胆囊切除术已成为一项成熟技术,我们对胆管损伤率随时间的变化趋势感兴趣。

目的

分析10年间腹腔镜胆囊切除术后转诊的胆管损伤的频率和解剖分布。

设计

回顾性病例系列研究。

单位

三级转诊肝胆科。

患者

因腹腔镜胆囊切除术后胆管损伤转诊至内镜逆行胰胆管造影(ERCP)科室进行诊断和治疗的患者。

干预

进行ERCP以诊断胆管损伤的程度和严重性。

主要观察指标

胆管损伤的类型和解剖结构、胆囊切除术的原因、损伤与诊断之间的平均时间、出现的症状、每年诊断的胆管损伤数与所做的总ERCP数之比。

结果

有87例胆管漏、28例伴有结石的漏、51例狭窄和17例完全胆管横断。每年每100例ERCP计算的胆管损伤率分别为:1994年0.84、1995年0.99、1996年1.36、1997年1.41、1998年1.03、1999年1.31、2000年0.84、2001年0.75、2002年1.15和2003年0.94。

局限性

单中心、回顾性分析,每年在转诊地区进行的胆囊切除术的分母未知,无法计算真正的胆管损伤率。

结论

在10年观察期内,三级转诊肝胆科胆囊切除术后胆管损伤的频率、解剖分布以及每年每100例ERCP的发生率保持稳定。

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