Department of Nursing, Faculty of Health Sciences, Universitas Alma Ata, Yogyakarta, Indonesia.
School of Nursing, College of Nursing, Taipei Medical University, Taipei, Taiwan.
PLoS One. 2021 Feb 9;16(2):e0246179. doi: 10.1371/journal.pone.0246179. eCollection 2021.
Reduced peak expiratory flow is a common physiological change in older individuals and age is an important predictor for sarcopenia. We analyzed nationwide survey data to determine the relationship between peak expiratory flow rate and sarcopenia in older Indonesians. Community-dwelling Indonesian individuals aged ≥60 years (n = 2422; mean age = 67.21 y) from the fifth-wave data of the Indonesian Family Life Survey was selected. Sarcopenia was diagnosed based on handgrip strength, gait speed, and appendicular skeletal muscle mass measurements. Peak expiratory flow rates (PEFRs) were categorized according to their percentage of predicted flow rates as <50%, 50% to 80%, and >80%. Confounders previously determined to be associated with sarcopenia occurrence were included. Sarcopenia prevalence was 50.25%. After adjustment for confounders, PEFRs of <50% and 50% to 80% were associated with an increased sarcopenia risk (odds ratio = 5.22 and 1.88, respectively) compared with PEFRs of >80%. Poor lung function was independently associated with sarcopenia occurrence. Future studies should explore the usefulness of PEFR as a risk factor of sarcopenia.
呼气峰值流量降低是老年人常见的生理变化,年龄是肌肉减少症的重要预测因素。我们分析了全国性调查数据,以确定印度尼西亚老年人呼气峰值流量率与肌肉减少症之间的关系。从印度尼西亚家庭生活调查的第五波数据中选择了年龄≥60 岁(n=2422;平均年龄=67.21 岁)的印度尼西亚社区居民。根据握力、步态速度和四肢骨骼肌质量测量值诊断肌肉减少症。呼气峰值流量率(PEFR)根据其预计流量率的百分比分为<50%、50%至 80%和>80%。纳入了先前确定与肌肉减少症发生相关的混杂因素。肌肉减少症的患病率为 50.25%。在校正混杂因素后,与 PEFR>80%相比,PEFR<50%和 50%至 80%与肌肉减少症风险增加相关(比值比分别为 5.22 和 1.88)。肺功能差与肌肉减少症的发生独立相关。未来的研究应该探讨 PEFR 作为肌肉减少症风险因素的有用性。