通过原位杂交将人类蛋白C基因（PROC）定位于染色体2q14----q21区域。
Assignment of the human protein C gene (PROC) to chromosome region 2q14----q21 by in situ hybridization.
作者信息
Kato A, Miura O, Sumi Y, Aoki N
机构信息
First Department of Medicine, Tokyo Medical and Dental University, Japan.
出版信息
Cytogenet Cell Genet. 1988;47(1-2):46-7. doi: 10.1159/000132503.
PMID:3356168
Abstract
The protein C gene (PROC) was mapped by in situ hybridization. A genomic DNA probe containing the first three exons was 3H-labeled by nick translation, and this was then hybridized in situ to human chromosome preparations. The results localize the gene to 2q14----q21.
摘要
通过原位杂交对蛋白C基因（PROC）进行了定位。一个包含前三个外显子的基因组DNA探针经缺口平移法用³H标记，然后将其与人类染色体标本进行原位杂交。结果将该基因定位到2q14----q21。
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