Rapoport Alexander, Guzhova Irina, Bernetti Lorenzo, Buzzini Pietro, Kieliszek Marek, Kot Anna Maria
Laboratory of Cell Biology, Institute of Microbiology and Biotechnology, University of Latvia, Jelgavas Str. 1-537, LV-1004 Riga, Latvia.
Laboratory of Cell Protective Mechanisms, Institute of Cytology, Russian Academy of Sciences, Tikhoretsky Avenue 4, 194064 Saint Petersburg, Russia.
Metabolites. 2021 Feb 6;11(2):92. doi: 10.3390/metabo11020092.
Carotenoids are an essential group of compounds that may be obtained by microbiological synthesis. They are instrumental in various areas of industry, medicine, agriculture, and ecology. The increase of carotenoids' demand at the global market is now essential. At the moment, the production of natural carotenoids is more expensive than obtaining their synthetic forms, but several new approaches/directions on how to decrease this difference were developed during the last decades. This review briefly describes the information accumulated until now about the beneficial effects of carotenoids on human health protection, their possible application in the treatments of various diseases, and their use in the food and feed industry. This review also describes some issues that are linked with biotechnological production of fungal and yeasts carotenoids, as well as new approaches/directions to make their biotechnological production more efficient.
类胡萝卜素是一类重要的化合物,可通过微生物合成获得。它们在工业、医学、农业和生态学的各个领域都发挥着重要作用。目前,全球市场对类胡萝卜素的需求日益增加。目前,天然类胡萝卜素的生产成本高于合成类胡萝卜素,但在过去几十年中,已经开发出了几种新的方法/方向来缩小这一差距。本综述简要介绍了迄今为止积累的有关类胡萝卜素对人体健康保护的有益作用、它们在各种疾病治疗中的可能应用以及它们在食品和饲料工业中的用途的信息。本综述还描述了与真菌和酵母类胡萝卜素的生物技术生产相关的一些问题,以及提高其生物技术生产效率的新方法/方向。