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新冠疫情封锁措施对马来西亚登革热传播的影响

Implications of the COVID-19 Lockdown on Dengue Transmission in Malaysia.

作者信息

Ong Song-Quan, Ahmad Hamdan, Mohd Ngesom Ahmad Mohiddin

机构信息

UOW Malaysia KDU Penang University College, 32, Jalan Anson, George Town, Penang 10400, Malaysia.

School of Computer Sciences, Universiti Sains Malaysia, Penang 11800, Malaysia.

出版信息

Infect Dis Rep. 2021 Feb 5;13(1):148-160. doi: 10.3390/idr13010016.

Abstract

We aim to investigate the effect of large-scale human movement restrictions during the COVID-19 lockdown on both the dengue transmission and vector occurrences. This study compared the weekly dengue incidences during the period of lockdown to the previous years (2015 to 2019) and a Seasonal Autoregressive Integrated Moving Average (SARIMA) model that expected no movement restrictions. We found that the trend of dengue incidence during the first two weeks (stage 1) of lockdown decreased significantly with the incidences lower than the lower confidence level (LCL) of SARIMA. By comparing the magnitude of the gradient of decrease, the trend is 319% steeper than the trend observed in previous years and 650% steeper than the simulated model, indicating that the control of population movement did reduce dengue transmission. However, starting from stage 2 of lockdown, the dengue incidences demonstrated an elevation and earlier rebound by four weeks and grew with an exponential pattern. We revealed that is the predominant species and demonstrated a strong correlation with the locally reported dengue incidences, and therefore we proposed the possible diffusive effect of the vector that led to a higher acceleration of incidence rate.

摘要

我们旨在研究新冠疫情封锁期间大规模人员流动限制对登革热传播和病媒出现情况的影响。本研究将封锁期间的每周登革热发病率与前几年(2015年至2019年)以及一个预期无流动限制的季节性自回归积分滑动平均(SARIMA)模型进行了比较。我们发现,封锁的前两周(第1阶段)登革热发病率呈显著下降趋势,发病率低于SARIMA的较低置信水平(LCL)。通过比较下降梯度的大小,该趋势比前几年观察到的趋势陡峭319%,比模拟模型陡峭650%,表明人口流动的控制确实减少了登革热传播。然而,从封锁的第2阶段开始,登革热发病率出现上升,并提前四周反弹,呈指数增长模式。我们发现 是主要物种,并且与当地报告的登革热发病率显示出很强的相关性,因此我们提出了病媒可能的扩散效应导致发病率加速上升的观点。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b9b/7985789/5b14ac083c9b/idr-13-00016-g001.jpg

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