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夹竹桃科植物的主要生物活性生物碱及其生物活性

Major Bioactive Alkaloids and Biological Activities of Species (Apocynaceae).

作者信息

Naidoo Clarissa Marcelle, Naidoo Yougasphree, Dewir Yaser Hassan, Murthy Hosakatte Niranjana, El-Hendawy Salah, Al-Suhaibani Nasser

机构信息

School of Life Sciences, Westville Campus, University of KwaZulu-Natal, Private Bag X54001, Durban 4000, South Africa.

Plant Production Department, College of Food and Agriculture Sciences, King Saud University, P.O. Box 2460, Riyadh 11451, Saudi Arabia.

出版信息

Plants (Basel). 2021 Feb 5;10(2):313. doi: 10.3390/plants10020313.

DOI:10.3390/plants10020313
PMID:33562893
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7915066/
Abstract

Several species belonging to the genus have been well researched and utilized for their wide-ranging biological activities. A few of the most prominent species include and . These species and many others within the genus often display pharmacological importance, which is habitually related to their chemical constituents. The secondary metabolites within the genus have demonstrated huge medicinal potential for the treatment of infections, pain, injuries, and various diseases. Regardless of the indispensable reports and properties displayed by spp., there remains a wide variety of plants that are yet to be considered or examined. Thus, an additional inclusive study on species within this genus is essential. The current review aimed to extensively analyze, collate, and describe an updated report of the current literature related to the major alkaloidal components and biological activities of species within the genus .

摘要

该属的几个物种因其广泛的生物活性而得到了充分的研究和利用。一些最著名的物种包括[具体物种1]和[具体物种2]。该属中的这些物种以及许多其他物种通常具有药理学重要性,这通常与其化学成分有关。该属中的次生代谢产物已显示出在治疗感染、疼痛、损伤和各种疾病方面的巨大药用潜力。尽管[该属物种]展示了不可或缺的报告和特性,但仍有各种各样的植物尚未得到考虑或研究。因此,对该属内物种进行额外的全面研究至关重要。本综述旨在广泛分析、整理和描述有关该属内物种主要生物碱成分和生物活性的当前文献的最新报告。

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1
and inhibitory effects of against venom.以及对毒液的抑制作用。 (注:原文表述不完整,翻译可能存在信息缺失导致语义不连贯的情况)
Saudi Pharm J. 2020 Jun;28(6):692-697. doi: 10.1016/j.jsps.2020.04.010. Epub 2020 Apr 25.
2
Extraction of Phenolic Compounds from Leaves and Their Effect on Oxidative Stress Markers in Diabetic Rats.从叶片中提取酚类化合物及其对糖尿病大鼠氧化应激标志物的影响。
Molecules. 2020 May 21;25(10):2391. doi: 10.3390/molecules25102391.
3
Preliminary evaluation of and antioxidative and antitumor activities of flavonoid extract of leaves in Ehrlich's lymphoma and Dalton's lymphoma ascites model.在艾氏淋巴瘤和道尔顿淋巴瘤腹水模型中对[植物名称]叶黄酮提取物的抗氧化和抗肿瘤活性的初步评估。 (你提供的原文中“and”重复,我按照合理推测进行了翻译,若有错误请你指出)
J Cancer Res Ther. 2020 Jan-Mar;16(1):78-87. doi: 10.4103/jcrt.JCRT_445_17.
4
Anti-cholinesterase potential of diverse botanical families from Malaysia: Evaluation of crude extracts and fractions from liquid-liquid extraction and acid-base fractionation.马来西亚多种植物科属的抗胆碱酯酶潜力:液液萃取和酸碱分步萃取的粗提物和馏分的评估。
J Ethnopharmacol. 2019 Dec 5;245:112160. doi: 10.1016/j.jep.2019.112160. Epub 2019 Aug 13.
5
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Bioorg Chem. 2019 Sep;90:103079. doi: 10.1016/j.bioorg.2019.103079. Epub 2019 Jun 19.
6
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J Ethnopharmacol. 2019 Jul 15;239:111863. doi: 10.1016/j.jep.2019.111863. Epub 2019 Apr 9.
7
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Phytomedicine. 2019 Feb 15;54:248-258. doi: 10.1016/j.phymed.2018.09.201. Epub 2018 Sep 18.
8
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9
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