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从开腹阑尾切除术时代迈向腹腔镜阑尾切除术时代:一项针对接受阑尾炎手术的成年患者的全国性队列研究。

Moving from an era of open appendectomy to an era of laparoscopic appendectomy: A nationwide cohort study of adult patients undergoing surgery for appendicitis.

机构信息

Department of Surgery North Zealand Hospital, Copenhagen University Hospital, Dyrehavevej 29, Hillerød 3400 Denmark.

National Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark.

出版信息

Scand J Surg. 2021 Dec;110(4):512-519. doi: 10.1177/1457496921992615. Epub 2021 Feb 9.

DOI:10.1177/1457496921992615
PMID:33563095
Abstract

BACKGROUND AND OBJECTIVE

During the last decades, laparoscopic surgery has been introduced as an alternative to open surgery. We aimed to examine to what extent laparoscopic surgery has replaced open surgery for appendicitis in an entire nation during the last two decades. Second, we examined the effects of shifting to laparoscopic surgery for appendicitis on different quality indicators such as length of postoperative stay and mortality. We also examined age as a predictor of 30-day mortality.

METHODS

During the period 2000 to 2015, all adult patients with appendicitis and surgical removal of the appendix were identified in the Danish National Patient Register. Demographics, type of surgery, time of surgery, and duration of postoperative stay were retrieved form Danish National Patient Register. Vital status was retrieved from the Danish Civil Registration System.

RESULTS

A total of 58,093 patients underwent surgery for appendicitis. In 2000, a total of 274 out of 3717 (7.4%) had a laparoscopic appendectomy, and the postoperative stay was 55 (iqr: 35-88) h and 30-day mortality was 0.91%. In 2015, a total of 3995 out of 4296 (93.0%) had a laparoscopic appendectomy, and the postoperative stay was 16 (iqr: 9-56) h and 30-day mortality was 0.40%. Age as a predictor of 30-day postoperative mortality had an area under the curve of 0.93 (95% confidence interval: 0.92; 0.94).

CONCLUSIONS

In Denmark, the standard surgical procedure for appendicitis has changed from open surgery to laparoscopic surgery during the period 2000-2015. At the same time, duration of postoperative stay and 30-day mortality has decreased.

摘要

背景和目的

在过去的几十年中,腹腔镜手术已被引入作为开放式手术的替代方法。我们旨在考察在过去二十年中,腹腔镜手术在整个国家范围内替代阑尾炎手术的程度。其次,我们考察了将阑尾炎手术转为腹腔镜手术对术后住院时间和死亡率等不同质量指标的影响。我们还考察了年龄作为 30 天死亡率预测因子的作用。

方法

在 2000 年至 2015 年期间,所有在丹麦国家患者登记处接受阑尾切除术的成年阑尾炎患者均被确定。从丹麦国家患者登记处获取人口统计学资料、手术类型、手术时间和术后住院时间。从丹麦民事登记系统获取生命状态。

结果

共有 58093 例患者接受了阑尾炎手术。2000 年,3717 例中有 274 例(7.4%)接受了腹腔镜阑尾切除术,术后住院时间为 55(iqr:35-88)小时,30 天死亡率为 0.91%。2015 年,4296 例中有 3995 例(93.0%)接受了腹腔镜阑尾切除术,术后住院时间为 16(iqr:9-56)小时,30 天死亡率为 0.40%。年龄作为 30 天术后死亡率的预测因子的曲线下面积为 0.93(95%置信区间:0.92;0.94)。

结论

在丹麦,2000-2015 年期间,阑尾炎的标准手术方法已从开放式手术转变为腹腔镜手术。与此同时,术后住院时间和 30 天死亡率均有所下降。

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