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对食物或营养素摄入量的血糖影响测量使用情况的全球评估。

Global evaluation of the use of glycaemic impact measurements to food or nutrient intake.

作者信息

Trumbo Paula R

机构信息

EAS Consulting Group, LLC, 1700 Diagonal Road Suite 750, Alexandria, VA22314, USA.

出版信息

Public Health Nutr. 2021 Aug;24(12):3966-3975. doi: 10.1017/S1368980021000616. Epub 2021 Feb 10.

Abstract

OBJECTIVE

Measures of glycaemic impact (e.g. postprandial glucose (PPG), oral glucose tolerance test (OGTT) and glycaemic index (GI)) are used by government health and regulatory agencies and public health associations around the world. The objective of this global review was to identify similarities and differences in the use of glycaemic impact measures for potential considerations for harmonisation.

DESIGN

A literature and internet search was conducted to identify country government agencies and health associations that provide guidance or recommendations for PPG, OGTT, GI and glycaemic load.

RESULTS

Based on this global review, the use of GI for food labelling (e.g. low GI) is limited and its use is voluntary. The application of OGTT as a diagnostic measurement of diabetes and gestational diabetes is widely used and in a consistent manner among the different regions of the world. Time-specific (e.g. 2 h) PPG is commonly used as a target not to exceed in individuals with diabetes and gestational diabetes. PPG is used by regulatory agencies for the substantiation of food labelling. There are differences, however, among regulatory agencies in the specific measure of PPG (i.e. PPG AUC v. peak PPG). Maximum targets for 2-h PPG for individuals with diabetes and gestational diabetes, ranging between 6 and 10 mmol/l, across countries suggest a potential consideration to harmonise PPG targets.

CONCLUSIONS

There is general consistency in the use and/or target levels of glycaemic impact measures; however, there is a potential need to investigate harmonisation strategies on certain aspects of glycaemic impact measures.

摘要

目的

全球各国政府卫生与监管机构以及公共卫生协会均采用血糖影响指标(如餐后血糖(PPG)、口服葡萄糖耐量试验(OGTT)和血糖生成指数(GI))。本次全球综述的目的是找出血糖影响指标使用方面的异同,以便为协调统一提供潜在参考。

设计

通过文献检索和互联网搜索,确定为PPG、OGTT、GI和血糖负荷提供指导或建议的国家政府机构和卫生协会。

结果

基于本次全球综述,GI用于食品标签标注(如低GI)的情况有限,且属于自愿使用。OGTT作为糖尿病和妊娠期糖尿病的诊断指标,在世界不同地区得到广泛且一致的应用。特定时间点(如2小时)的PPG通常被用作糖尿病和妊娠期糖尿病患者的血糖上限目标。监管机构利用PPG来证实食品标签内容。然而,不同监管机构在PPG的具体测量指标(即PPG曲线下面积与PPG峰值)上存在差异。各国糖尿病和妊娠期糖尿病患者2小时PPG的最高目标值在6至10 mmol/L之间,这表明有必要考虑协调统一PPG目标值。

结论

血糖影响指标的使用和/或目标水平总体上具有一致性;然而,在血糖影响指标的某些方面可能需要研究协调统一策略。

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本文引用的文献

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Standards of medical care for type 2 diabetes in China 2019.中国 2019 年 2 型糖尿病医学诊疗标准。
Diabetes Metab Res Rev. 2019 Sep;35(6):e3158. doi: 10.1002/dmrr.3158. Epub 2019 May 29.
2
14. Management of Diabetes in Pregnancy: .14. 妊娠期间糖尿病的管理: 。
Diabetes Care. 2019 Jan;42(Suppl 1):S165-S172. doi: 10.2337/dc19-S014.
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Type 2 diabetes in Brazil: epidemiology and management.巴西的2型糖尿病:流行病学与管理
Diabetes Metab Syndr Obes. 2015 Jan 5;8:17-28. doi: 10.2147/DMSO.S72542. eCollection 2015.

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