宏量营养素质量指数与伊朗成年人代谢综合征及其组分风险的关系。

Macronutrients quality indices and risk of metabolic syndrome and its components in Iranian adults.

机构信息

Nutrition and Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Department of Nutrition, School of Public Health, Iran University of Medical Sciences, Tehran, Iran.

出版信息

BMC Cardiovasc Disord. 2024 Feb 26;24(1):126. doi: 10.1186/s12872-024-03779-1.

DOI:10.1186/s12872-024-03779-1

PMID:38408923

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10898212/

Abstract

BACKGROUND/AIM: Evidence from recent studies suggested that the quality of dietary macronutrients can play a possible role in predicting the risk of metabolic disorders. In the current study, we aimed to assess the association of carbohydrate quality index (CQI) and protein score with the risk of metabolic syndrome (MetS) in Iranian adults.

METHODS

This prospective study was conducted within the framework of the Tehran Lipid and Glucose Study on 1738 individuals aged between 40 and 70 years old, who were followed up for a mean of 6.1 years. A food frequency questionnaire was used to determine CQI and protein scores. The multivariable adjusted Cox regression model was used to calculate the hazard ratio (HR) of MetS across quartiles of protein score and CQI, and its components.

RESULTS

The mean ± standard deviation (SD) age and body mass index of the study population (42.5% men) were 49.3 ± 7.5 years and 27.0 ± 4.0 kg/m, respectively. Mean ± SD scores of CQI and protein for all participants were 12.6 ± 2.4 and 10.3 ± 3.5, respectively. During the study follow-up, 834(48.0%) new cases of MetS were ascertained. In the multivariable-adjusted model, the risk of MetS was decreased across quartiles of CQI (HR = 0.83;95%CI:0.69-1.00, P=0.025) and protein score (HR = 0.75; 95% CI:0.60-0.94, P=0.041). Also, Of CQI components, the whole grain/total grains ratio showed a significant inverse association with the risk of MetS (HR = 0.75;95%CI:0.60-0.94, P=0.012).

CONCLUSION

Our findings revealed that a dietary pattern with higher CQI and protein score may be related to a reduced risk of MetS in adults.

摘要

背景/目的：最近的研究证据表明，膳食宏量营养素的质量可能在预测代谢紊乱风险方面发挥作用。本研究旨在评估碳水化合物质量指数（CQI）和蛋白质评分与伊朗成年人代谢综合征（MetS）风险之间的关系。

方法

这项前瞻性研究是在德黑兰血脂和血糖研究的框架内进行的，共有 1738 名年龄在 40 至 70 岁之间的个体参与，平均随访时间为 6.1 年。使用食物频率问卷来确定 CQI 和蛋白质评分。使用多变量调整的 Cox 回归模型来计算蛋白质评分和 CQI 四分位数与 MetS 之间的风险比（HR），以及其成分。

结果

研究人群（42.5%为男性）的平均年龄为 49.3±7.5 岁，平均 BMI 为 27.0±4.0kg/m2。所有参与者的 CQI 和蛋白质平均得分分别为 12.6±2.4 和 10.3±3.5。在研究随访期间，确定了 834 例（48.0%）新的 MetS 病例。在多变量调整模型中，CQI 四分位数（HR=0.83；95%CI：0.69-1.00，P=0.025）和蛋白质评分（HR=0.75；95%CI：0.60-0.94，P=0.041）的 MetS 风险降低。此外，在 CQI 成分中，全谷物/总谷物比值与 MetS 风险呈显著负相关（HR=0.75；95%CI：0.60-0.94，P=0.012）。