Immunology Department, Weizmann Institute of Science, Rehovot, 7610001, Israel; 1st Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Immunology Department, Weizmann Institute of Science, Rehovot, 7610001, Israel; Department of Surgery, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Trends Mol Med. 2021 Apr;27(4):298-301. doi: 10.1016/j.molmed.2021.01.003. Epub 2021 Feb 6.
Over the past 15 years, the research community has witnessed unprecedented progress in microbiome research. We review this increasing knowledge and first attempts of its clinical application, and also limitations and challenges faced by the research community, in mechanistically understanding host-microbiome interactions and integrating these insights into clinical practice.
在过去的 15 年中,研究界见证了微生物组研究的空前进展。我们回顾了这方面日益增长的知识和临床应用的初步尝试,以及研究界在从机制上理解宿主-微生物组相互作用并将这些见解整合到临床实践中所面临的限制和挑战。