Suppr超能文献

类风湿关节炎和脊柱关节炎男性患者与对照组的下尿路症状比较。

Lower urinary tract symptoms in rheumatoid arthritis and spondyloarthritis male patients versus controls.

机构信息

Rheumatology department, Mongi Slim Hospital, La Marsa, Tunisia.

Faculty of Medicin, Tunis El Manar University, Tunis, Tunisia.

出版信息

Rom J Intern Med. 2021 May 8;59(2):134-140. doi: 10.2478/rjim-2020-0041. Print 2021 Jun 1.

Abstract

We aimed to evaluate the severity of lower urinary tract symptoms (LUTS) in rheumatoid arthritis (RA) and spondyloarthritis (SpA) male patient versus control, then to determine the relation of LUTS with rheumatic diseases (RD) characteristics and with erectile dysfunction (ED). We conducted a cross-sectional case control study including 50 men with RA or SpA and 50 healthy controls. LUTS were evaluated by the International Prostate Symptom Score (IPSS). LUTS bother was evaluated by the Quality of life (QoL) score, which ranges from 0 to 6. LUTS bother was considered if QoL score exceeded 2. Moreover, erectile function was assessed by the International Index of Erectile Function-5 (IIEF5) (ED if score < 21). LUTS were significantly more severe in RD patients than controls (p = 0.03). However, there was no difference between the two groups in LUTS bother (QoL) (p = 0.2). Comparing RA and SpA showed no difference as to the severity of LUTS or effect of bother on QoL (p = 0.13, p = 0.5). The prevalence of ED in RD patients was not significantly higher than controls (80% versus 70%; p = 0.2).There were also no differences either between RA and SpA groups (p = 0.74).The severity of LUTS for patients with RD (RA and SpA) was significantly associated with age (p = 0.001), age at disease onset (p = 0.002) and ED (p = 0.008). According to our study, men with RD seem to be exposed to more severe LUTS than controls. Also, the severity of LUTS was associated with ED, age of patients and the age of disease onset.

摘要

我们旨在评估类风湿关节炎(RA)和脊柱关节炎(SpA)男性患者与对照组相比下尿路症状(LUTS)的严重程度,然后确定 LUTS 与风湿性疾病(RD)特征的关系以及与勃起功能障碍(ED)的关系。我们进行了一项横断面病例对照研究,纳入了 50 名 RA 或 SpA 男性患者和 50 名健康对照者。LUTS 采用国际前列腺症状评分(IPSS)进行评估。LUTS 困扰程度采用生活质量(QoL)评分进行评估,范围为 0 至 6 分。如果 QoL 评分超过 2 分,则认为存在 LUTS 困扰。此外,采用国际勃起功能指数-5(IIEF5)评估勃起功能(如果评分 < 21 则为 ED)。与对照组相比,RD 患者的 LUTS 明显更严重(p = 0.03)。然而,两组之间的 LUTS 困扰程度(QoL)无差异(p = 0.2)。比较 RA 和 SpA 发现,LUTS 的严重程度或对 QoL 的困扰程度无差异(p = 0.13,p = 0.5)。RD 患者的 ED 患病率并不明显高于对照组(80%比 70%;p = 0.2)。RA 和 SpA 两组之间也无差异(p = 0.74)。RD 患者(RA 和 SpA)的 LUTS 严重程度与年龄(p = 0.001)、疾病发病年龄(p = 0.002)和 ED(p = 0.008)显著相关。根据我们的研究,RD 男性似乎比对照组更容易出现更严重的 LUTS。此外,LUTS 的严重程度与 ED、患者年龄和疾病发病年龄相关。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验