Song Jian, Shao Qiang, Tian Ye, Na Yan-qun, Chen Shan, Wang Yi, Zhang Xiang-hua, Hong Bao-fa, Sun Wen-xue, Diao Ying-zhi
Department of Urology, Beijing Friendship Hospital, Capital Medical Universty, Beijing 100050, China.
Zhonghua Yi Xue Za Zhi. 2011 Oct 18;91(38):2706-9.
To survey the incidence of lower urinary tract symptoms (LUTS) and erectile dysfunction (ED) in males aged ≥ 50 years and explore the correlation between LUTS and ED.
A cross-sectional study was performed at Beijing communities in 1644 males aged over 50 years. The International Index of Erectile Function-5 (IIEF-5) and International Prostate Symptom Score (IPSS) were recorded. Pearson's χ(2) test and Spearman correlation coefficients were used to analyze the results of IPSS, LUTS and their correlations with ED.
The mean age was 64.5 years old (range: 50-93), the mean value of IPSS(9.9 ± 8.2), the prevalence of mild, moderate and severe LUTS 49.2% (809/1644), 36.4% (599/1644) and 14.4% (236/1644) respectively. The mean value of IIEF was (9.4 ± 8.6), the total incidence of ED 90.5% (1487/1644) and the incidence of ED of mild, moderate and severe LUTS 85.7% (694/809), 93.7% (561/599) and 97.9% (231/236) respectively. The total IIEF-5 score was found significantly correlated with the total IPSS score (r = -0.335, P < 0.01), the obstructive symptoms (r = -0.276, P < 0.01)and irritative symptoms (r = -0.326, P < 0.01). The severity of LUTS was correlated with the severity of ED (r = 0.304, P < 0.01). Correlations also existed between age and total IPSS score(r = 0.388, P < 0.01), LUTS severity (r = 0.457, P < 0.01), total IIEF score (r = -0.533, P < 0.01) or ED severity (r = 0.529, P < 0.01).
The incidence of LUTS or ED in aging males increases with age. The severity of ED is positively correlated with the severity of LUTS. Irritative and obstructive symptoms influence the occurrence of ED in aging males.
调查年龄≥50岁男性下尿路症状（LUTS）和勃起功能障碍（ED）的发生率，并探讨LUTS与ED之间的相关性。
在北京社区对1644名50岁以上男性进行横断面研究。记录国际勃起功能指数-5（IIEF-5）和国际前列腺症状评分（IPSS）。采用Pearson卡方检验和Spearman相关系数分析IPSS、LUTS的结果及其与ED的相关性。
平均年龄为64.5岁（范围：50 - 93岁），IPSS平均值为（9.9±8.2），轻度、中度和重度LUTS的患病率分别为49.2%（809/1644）、36.4%（599/1644）和14.4%（236/1644）。IIEF平均值为（9.4±8.6），ED总发生率为90.5%（1487/1644），轻度、中度和重度LUTS患者的ED发生率分别为85.7%（694/809）、93.7%（561/599）和97.9%（231/236）。发现IIEF-5总分与IPSS总分显著相关（r = -0.335，P < 0.01），与梗阻性症状（r = -0.276，P < 0.01）和刺激性症状（r = -0.326，P < 0.01）也显著相关。LUTS的严重程度与ED的严重程度相关（r = 0.304，P < 0.01）。年龄与IPSS总分（r = 0.388，P < 0.01）、LUTS严重程度（r = 0.457，P < 0.01）、IIEF总分（r = -0.533，P < 0.01）或ED严重程度（r = 0.529，P < 0.01）之间也存在相关性。
老年男性LUTS或ED的发生率随年龄增加而升高。ED的严重程度与LUTS的严重程度呈正相关。刺激性和梗阻性症状影响老年男性ED的发生。
