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下尿路症状(LUTS)与勃起功能障碍(ED)之间的相关性:来自墨西哥城男性的一项调查(MexiLUTS)结果

The correlation between lower urinary tract symptoms (LUTS) and erectile dysfunction (ED): results from a survey in males from Mexico City (MexiLUTS).

作者信息

Gonzalez-Sanchez Benjamin, Cendejas-Gomez Jesus, Alejandro Rivera-Ramirez J, Herrera-Caceres Jaime O, Olvera-Posada Daniel, Villeda-Sandoval Christian I, Castillejos-Molina Ricardo A, Feria-Bernal Guillermo, Garcia-Mora Arturo, Rodriguez-Covarrubias Francisco

机构信息

Department of Urology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga 15, Col. Seccion XVI, Tlalpan, 14080, Mexico City, Mexico.

出版信息

World J Urol. 2016 Jul;34(7):979-83. doi: 10.1007/s00345-015-1703-4. Epub 2015 Oct 14.

Abstract

INTRODUCTION

ED and LUTS affect a high proportion of male population. Although Hispanics are suspected to have a higher risk of experiencing LUTS, detailed information on its frequency and association with ED in this population is scarce.

OBJECTIVE

To determine the frequency of LUTS and ED, and its correlation in Mexican males.

METHODS

A cross-sectional analytical survey was answered by 1041 men. It included the International Prostate Symptom Score and the quality of life question (IPSS/QoL); International Index of Erectile Function (IIEF-5); the short form of the International Consultation of Incontinence Questionnaire (ICIQ-SF); and demographic data. For the analysis, we divided our population into 2 groups (18-39 and 40 and older), and then an exploratory correlation analysis was performed to search for significant differences among IPSS severity groups, and finally a multivariate regression model was applied.

RESULTS

Mean age was 48.6 ± 14.5 years. One hundred twenty-three individuals (11.8 %) were asymptomatic, and 611 (58.7 %) had mild, 226 (21.7 %) had moderate, and 81 (7.8 %) had severe IPSS score. The most common symptoms were nocturia (72.4 %), increased urinary frequency (58.3 %), and slow urinary stream (42.6 %). Two hundred fifty-eight (24.7 %) complained of incontinence. Of 765 individuals, 484(63.2 %) reported some degree of ED. Severe LUTS, DM, and age were independent risk factors for ED severity.

CONCLUSION

LUTS and ED may represent one of the largest sources of morbidity in our population, and their association was demonstrated. Awareness on these entities should be raised, and further research is required to determine the higher frequency of LUTS and ED in Hispanics.

摘要

引言

勃起功能障碍(ED)和下尿路症状(LUTS)影响着很大比例的男性人群。尽管有推测认为西班牙裔男性出现LUTS的风险较高,但关于该人群中LUTS的发生率及其与ED的关联的详细信息却很匮乏。

目的

确定墨西哥男性中LUTS和ED的发生率及其相关性。

方法

1041名男性参与了一项横断面分析调查。调查内容包括国际前列腺症状评分和生活质量问题(IPSS/QoL)、国际勃起功能指数(IIEF-5)、国际尿失禁咨询问卷简表(ICIQ-SF)以及人口统计学数据。为了进行分析,我们将研究人群分为两组(18 - 39岁和40岁及以上),然后进行探索性相关分析以寻找IPSS严重程度组之间的显著差异,最后应用多元回归模型。

结果

平均年龄为48.6 ± 14.5岁。123人(11.8%)无症状,611人(58.7%)有轻度症状,226人(21.7%)有中度症状,81人(7.8%)有重度IPSS评分。最常见的症状是夜尿(72.4%)、尿频增加(58.3%)和尿流缓慢(42.6%)。258人(24.7%)主诉有尿失禁。在765名个体中,484人(63.2%)报告有某种程度的ED。重度LUTS、糖尿病和年龄是ED严重程度的独立危险因素。

结论

LUTS和ED可能是我们人群中最大的发病原因之一,且它们之间的关联已得到证实。应提高对这些疾病的认识,还需要进一步研究以确定西班牙裔人群中LUTS和ED的更高发生率。

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