Mediprobe Research Inc, London, Canada.
Department of Medicine, Division of Dermatology, University of Toronto School of Medicine, Toronto, Canada.
J Dermatolog Treat. 2022 May;33(3):1312-1318. doi: 10.1080/09546634.2021.1887442. Epub 2021 Feb 21.
Androgenetic alopecia (AGA) is the most common cause of hair loss in men and women. Artificial hair implantation is considered an alternative treatment when the donor area is depleted or unsuitable for hair transplantation. The use of artificial hair implants remains controversial, particularly because this practice has been banned by the US FDA.
To summarize various aspects of artificial hair implantation.
We discuss the history of artificial hair implantation, development of new biocompatible fibers (Biofibre, Nido Z-type), patient eligibility for this treatment, implantation technique, follow-up, immune response to the implanted fibers, and post-implantation complications. We performed a methodological quality assessment of the clinical studies that investigated artificial hair implantation using the Canadian Institute of Health Economics (IHE) Quality Appraisal Tool for Case Series (Interventional).
Although the studies evaluating the use of artificial hair fibers appear promising, the methodological quality of most of them was between 'poor' and 'fair', due to lack of randomization, absence of control groups, improper study design, and inappropriate outcome measures.
Artificial hair implantation has been received with skepticism among physicians due to the complications reported. Further high-quality research needs to be performed to ascertain the safety and efficacy of artificial hair implantation.
雄激素性脱发（AGA）是男性和女性最常见的脱发原因。当供体区域枯竭或不适合毛发移植时，人工毛发植入被认为是一种替代治疗方法。然而，人工毛发植入的使用仍然存在争议，特别是因为美国 FDA 已经禁止了这种做法。
总结人工毛发植入的各个方面。
我们讨论了人工毛发植入的历史、新型生物相容性纤维（Biofibre、Nido Z 型）的发展、患者接受这种治疗的资格、植入技术、随访、对植入纤维的免疫反应以及植入后的并发症。我们使用加拿大卫生经济研究所（IHE）病例系列（干预）质量评估工具对研究人工毛发植入的临床研究进行了方法学质量评估。
尽管评估人工毛发纤维使用的研究似乎很有前景，但由于缺乏随机化、没有对照组、研究设计不当和不适当的结果测量，大多数研究的方法学质量介于“差”和“一般”之间。
由于报道的并发症，医生对人工毛发植入持怀疑态度。需要进行更多高质量的研究，以确定人工毛发植入的安全性和有效性。
