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两个基布兹爆发肺炎支原体肺炎:一项临床与流行病学研究。

An outbreak of Mycoplasma pneumoniae pneumonia in two kibbutzim: a clinical and epidemiologic study.

作者信息

Leibowitz Z, Schvartzman P, Epstein L, Lis I, Naot Y

机构信息

Department of Family Medicine, Central Emek Hospital, Afula, Israel.

出版信息

Isr J Med Sci. 1988 Feb;24(2):88-92.

PMID:3356539
Abstract

During a period a 9 months, 125 individuals with pneumonia due to infection with Mycoplasma pneumoniae were identified among 1,242 individuals in two Israeli kibbutzim. The monthly incidence of M. pneumoniae pneumonia (MPP) was 13.3/1,000 population. Of those infected, 93 (74.4%) were under the age of 18 years. The clinical course of MPP was mostly benign. The prominent signs and symptoms of disease were cough (100%), fine respiratory crepitations (77%), fever (37%), and diminished breathing sounds (25%) above affected lung areas. Leukocytosis was rare (9.6%); however, eosinophilia was observed in 23% of 53 tests performed. Exacerbations of bronchial asthma was observed among 36% of 11 patients with a previous history of asthma. The average duration of disease was 13.5 days, under treatment. A recurrence rate of 11.2% was noted among all MPP patients, with a very high (42.3%) rate among patients treated with cotrimoxazole. All patients with recurrent pneumonia were children under the age of 10 years.

摘要

在9个月的时间里,在以色列的两个基布兹的1242人中,发现了125例因肺炎支原体感染而患肺炎的患者。肺炎支原体肺炎(MPP)的月发病率为13.3/1000人口。在这些感染者中,93例(74.4%)年龄在18岁以下。MPP的临床病程大多为良性。该病的突出体征和症状为咳嗽(100%)、肺部细湿啰音(77%)、发热(37%)以及患侧肺部呼吸音减弱(25%)。白细胞增多症少见(9.6%);然而,在53次检测中有23%观察到嗜酸性粒细胞增多。在11例有哮喘病史的患者中,36%出现支气管哮喘加重。接受治疗的患者疾病平均持续时间为13.5天。所有MPP患者的复发率为11.2%,在接受复方新诺明治疗的患者中复发率非常高(42.3%)。所有复发性肺炎患者均为10岁以下儿童。

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