Boschert K R, Allison N, Allen T L, Griffin R B
College of Veterinary Medicine, Mississippi State University, MS 39762.
J Am Vet Med Assoc. 1988 Mar 15;192(6):791-2.
Bacillus piliformis infection (Tyzzer's disease) was diagnosed in a 7-year-old spayed dog that had icterus, hepatosplenomegaly, and polyuria. Hematology revealed regenerative anemia, leukocytosis, lymphopenia, and thrombocytopenia. Serum chemical analyses indicated hypocalcemia, high alkaline phosphatase activity, hypoalbuminemia, and hyperglobulinemia. At necropsy, the liver was stippled with gray-white focal lesions. Microscopically, the liver lesions were necrotic and inflammatory. Warthin-Starry-stained sections revealed rod-shaped bacteria in crisscrossing patterns characteristic of B piliformis. This dog was considerably older than dogs previously reported to have Tyzzer's disease and had a concurrent systemic hyphomycosis, suggesting it had been immunocompromised.
一只7岁已绝育的犬被诊断患有梨形芽孢杆菌感染（泰泽氏病），该犬出现黄疸、肝脾肿大和多尿症状。血液学检查显示有再生性贫血、白细胞增多、淋巴细胞减少和血小板减少。血清化学分析表明存在低钙血症、碱性磷酸酶活性升高、低白蛋白血症和高球蛋白血症。尸检时，肝脏布满灰白色局灶性病变。显微镜下，肝脏病变为坏死性和炎症性。经沃辛-斯塔瑞染色的切片显示有呈梨形芽孢杆菌特有的交叉状排列的杆状细菌。这只犬比先前报道患有泰泽氏病的犬年龄大得多，并且同时患有全身性丝状菌病，提示其存在免疫功能低下。
