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解码抗肿瘤免疫的遗传基础。

Decoding the genetic basis of anti-tumor immunity.

机构信息

Peking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, China.

Peking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, China; BIOPIC, Beijing Advanced Innovation Center for Genomics, School of Life Sciences, Peking University, Beijing 100871, China.

出版信息

Immunity. 2021 Feb 9;54(2):199-201. doi: 10.1016/j.immuni.2021.01.005.

Abstract

Substantial variations of tumor immune properties exist among cancer patients, but the contributing factors underlying those variations are poorly understood. In this issue of Immunity, Sayaman et al. uncover associations between germline genetic variants and tumor immune properties, revealing candidate causal genes.

摘要

肿瘤患者的肿瘤免疫特性存在很大差异,但这些差异的潜在影响因素尚未被充分了解。在本期《Immunity》杂志中,Sayaman 等人发现了种系遗传变异与肿瘤免疫特性之间的关联,揭示了候选的因果基因。

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