Sakaguchi T, Sakaguchi S, Nakamura I, Kudo Y, Ichiman Y, Yoshida K
Department of Hygiene, Marianna University School of Medicine, Kawasaki, Japan.
J Clin Microbiol. 1988 Mar;26(3):600-1. doi: 10.1128/jcm.26.3.600-601.1988.
Nonenterotoxigenic and nonhemolytic strains of Staphylococcus aureus exhibited a positive reaction in the mouse intestinal loop assay except for a strain negative for the egg yolk reaction. Edema and swelling in all positive loops, increased bacterial cell numbers within intestinal loops, and extremely close adhesion to or inclusion of numerous bacterial cells in HeLa cells after inoculation of the strains were observed. These results suggest a possible invasive ability of the strains.
除了一株对蛋黄反应呈阴性的菌株外,金黄色葡萄球菌的非产肠毒素和非溶血菌株在小鼠肠袢试验中呈阳性反应。观察到所有阳性肠袢出现水肿和肿胀、肠袢内细菌细胞数量增加,并且在接种菌株后HeLa细胞中出现大量细菌细胞与HeLa细胞紧密粘附或被其吞噬的现象。这些结果表明这些菌株可能具有侵袭能力。