Dolan D F, Nuttall A L
Kresge Hearing Research Institute, University of Michigan, Ann Arbor 48109-0506.
J Acoust Soc Am. 1988 Mar;83(3):1081-6. doi: 10.1121/1.396052.
Cochlear whole-nerve response (CAP) intensity functions were recorded from the guinea pig round window. The intensity functions were obtained in the presence of masking noise, with electrical stimulation of the crossed olivocochlear bundle (COCB), and the combination of masking noise and COCB stimulation. Electrical stimulation of the COCB produced the expected reduction of CAP magnitude for low- to moderate-intensity tone bursts. Masking noise produced reductions in CAP magnitude over the whole signal intensity range used in this study. The combination of electrical stimulation of the COCB with the masking noise produced CAP magnitude changes graded between reduction and enhancement dependent on signal and masker levels. In general, at low signal levels, the masked CAP magnitude is reduced compared to the masked alone condition. At high signal levels, the masked CAP is increased in magnitude. These results confirm and extend the earlier observations of Nieder and Nieder [Exp. Neurol. 28, 174-188 (1970); also, Nature 227, 184-185 (1970)].
从豚鼠圆窗记录耳蜗全神经反应（CAP）强度函数。强度函数是在存在掩蔽噪声、电刺激交叉橄榄耳蜗束（COCB）以及掩蔽噪声与COCB刺激相结合的情况下获得的。电刺激COCB导致低至中等强度的短音脉冲串的CAP幅度出现预期的降低。掩蔽噪声在本研究使用的整个信号强度范围内降低了CAP幅度。COCB电刺激与掩蔽噪声相结合产生的CAP幅度变化根据信号和掩蔽器水平在降低和增强之间分级。一般来说，在低信号水平下，与单独掩蔽条件相比，掩蔽后的CAP幅度降低。在高信号水平下，掩蔽后的CAP幅度增加。这些结果证实并扩展了Nieder和Nieder早期的观察结果[《实验神经学》28，174 - 188（1970年）；此外，《自然》227，184 - 185（1970年）]。
