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临床和环境来源的耐甲氧西林金黄色葡萄球菌中毒力基因和SCCmec类型的分布:来自印度阿萨姆邦社区的一项研究

Distribution of virulence genes and SCCmec types among methicillin-resistant Staphylococcus aureus of clinical and environmental origin: a study from community of Assam, India.

作者信息

Bhowmik Deepshikha, Chetri Shiela, Das Bhaskar Jyoti, Dhar Chanda Debadatta, Bhattacharjee Amitabha

机构信息

Department of Microbiology, Assam University, Silchar, Assam, India.

Department of Microbiology, Silchar Medical College and Hospital, Silchar, Assam, India.

出版信息

BMC Res Notes. 2021 Feb 10;14(1):58. doi: 10.1186/s13104-021-05473-3.

DOI:10.1186/s13104-021-05473-3
PMID:33568186
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7876809/
Abstract

OBJECTIVE

This study was designed to discover the dissemination of virulence genes in Methicillin-resistant Staphylococcus aureus from clinical, community and environmental settings.

RESULTS

This study includes 1165 isolates collected from hospital, community and environmental settings. Among them sixty three were confirmed as MRSA with varied SCCmec types viz; type I, type II, type III, type IV, type V, type VI, type VII, type VIII and type XII. The virulence gene such as sea (n = 54), seb (n = 21), eta (n = 27), etb (n = 2), cna (n = 24), ica (n = 2) and tst (n = 30) was also revealed from this study. The study underscores coexistence of resistance cassette and virulence genes among clinical and environment isolates which is first of its kind from this part of the world.

摘要

目的

本研究旨在发现耐甲氧西林金黄色葡萄球菌毒力基因在临床、社区和环境样本中的分布情况。

结果

本研究纳入了从医院、社区和环境样本中收集的1165株菌株。其中63株被确认为耐甲氧西林金黄色葡萄球菌,具有多种SCCmec类型,即I型、II型、III型、IV型、V型、VI型、VII型、VIII型和XII型。本研究还发现了毒力基因,如sea(n = 54)、seb(n = 21)、eta(n = 27)、etb(n = 2)、cna(n = 24)、ica(n = 2)和tst(n = 30)。该研究强调了耐药盒与毒力基因在临床和环境分离株中的共存,这在世界该地区尚属首次。

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An array of multiplex PCR assays for detection of staphylococcal chromosomal cassette mec (SCCmec) types among staphylococcal isolates.
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