Derbie Awoke, Mekonnen Daniel, Misgan Eyaya, Alemu Yihun Mulugeta, Woldeamanuel Yimtubezinash, Abebe Tamrat
Department of Medical Microbiology, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia.
Centre for Innovative Drug Development and Therapeutic Trials for Africa (CDT-Africa), Addis Ababa University, Addis Ababa, Ethiopia.
Infect Agent Cancer. 2021 Feb 10;16(1):11. doi: 10.1186/s13027-021-00350-x.
Cervical cancer is one of the leading causes of malignancies among women in Ethiopia. Knowing the disease could empower women to make an informed decision regarding participation with cervical cancer prevention strategies. There is scarcity of compiled data in the field. Therefore, this systematic review aimed to provide an overview of knowledge about cervical cancer among Ethiopian women.
We conducted a systematic review of peer-reviewed articles on the knowledge of cervical cancer. Articles were systematically searched using comprehensive search strings from PubMed/Medline, SCOPUS, and grey literature from Google Scholar. Two reviewers assessed study eligibility, extracted data, and the risk of bias independently. Meta-analysis was performed using STATA v 14 to pool the overall knowledge of the women about cervical cancer.
We included 26 articles published between 2013 and 2020 covering a total of 14,549 participants. All the included articles had good methodological quality. The proportion of participants who had heard of cervical cancer varied from 4.6 to 87.7% with the pooled estimate at 56% (95% CI: 47-66). Similarly, the proportion of participants who knew that HPV is the main cause of cervical cancer lied between 0 and 49.7% with the pooled result at 21% (95% CI: 13-30). Likewise, the pooled prevalence to identify at least one risk factor, one symptom of cervical cancer and ever heard of cervical cancer screening was gauged at 52% (95% CI: 39-64), 43% (95% CI: 26-60), and 39% (95% CI: 24-55), respectively. The overall pooled prevalence of good knowledge about cervical cancer was at 43% (95% CI: 33-53). On top of this, the prevalence of previous screening practice among the participants was at 14% (95% CI: 9-20).
Knowledge about cervical cancer among Ethiopian women is quite poor. Therefore, health education to provide sufficient and unbiased information about HPV and cervical cancer in general is required to the public.
宫颈癌是埃塞俄比亚女性恶性肿瘤的主要病因之一。了解这种疾病能够使女性在参与宫颈癌预防策略方面做出明智的决定。该领域缺乏汇编数据。因此，本系统评价旨在概述埃塞俄比亚女性对宫颈癌的了解情况。
我们对关于宫颈癌知识的同行评审文章进行了系统评价。使用来自PubMed/Medline、SCOPUS的综合检索词以及谷歌学术的灰色文献对文章进行系统检索。两名评审员独立评估研究的纳入资格、提取数据并评估偏倚风险。使用STATA v 14进行荟萃分析，以汇总女性对宫颈癌的总体了解情况。
我们纳入了2013年至2020年发表的26篇文章，共涉及14549名参与者。所有纳入的文章都具有良好的方法学质量。听说过宫颈癌的参与者比例在4.6%至87.7%之间，汇总估计值为56%（95%置信区间：47 - 66）。同样，知道人乳头瘤病毒（HPV）是宫颈癌主要病因的参与者比例在0至49.7%之间，汇总结果为21%（95%置信区间：13 - 30）。同样，识别出至少一种宫颈癌危险因素、一种症状以及听说过宫颈癌筛查的汇总患病率分别为52%（95%置信区间：39 - 64）、43%（95%置信区间：26 - 60）和39%（95%置信区间：24 - 55）。对宫颈癌有充分了解的总体汇总患病率为43%（95%置信区间：33 - 53）。除此之外，参与者中既往筛查的患病率为14%（95%置信区间：9 - 20）。
埃塞俄比亚女性对宫颈癌的了解相当匮乏。因此，需要向公众提供关于HPV和宫颈癌的充分且无偏差信息的健康教育。
