Pediatric Dentistry and Dental Public Health Department, Faculty of Dental Medicine, Lebanese University, Beirut, Lebanon, Phone: +9613765 806, e-mail:
Pediatric Dentistry and Dental Public Health Department, Faculty of Dental Medicine, Lebanese University, Beirut, Lebanon.
J Contemp Dent Pract. 2020 Sep 1;21(9):1012-1017.
We checked in this study the correlation between total immunoglobulin A (IgA) and (SM) levels in saliva derived from Lebanese children with inappropriate eating habits and showing early childhood caries (ECC).
Sixty Lebanese preschool children with similar alimentation were included in this study and divided into two groups. Group I included children having 0 cavities where group II contained children having ECC. We measured the SM and IgA levels collected from saliva and dental plaque.
We observed a significant difference in SM levels between the two groups ( < 0.001). There was a marginal correlation between salivary total IgA and SM collected from dental plaque ( = 0.33, = 0.077). However, no significant correlation was detected between total salivary IgA and salivary SM ( = 0.35).
This study suggests the absence of significant relationship between salivary markers of immune system and the development of ECC.
Early childhood caries is a public dental health problem that has been affecting preschool children all over the world. Its prevention must be a priority for all professionals in the medical and dental community. This study highlights the absence of correlation between total IgA and SM collected from the saliva. This does not completely exclude the preventive role of salivary immune components, but further studies are required to better understand this relationship.
本研究旨在检查黎巴嫩有不良饮食习惯且出现早期儿童龋（ECC）的儿童唾液中总免疫球蛋白 A（IgA）和分泌型免疫球蛋白 A（SM）水平之间的相关性。
本研究纳入了 60 名具有相似饮食习惯的黎巴嫩学龄前儿童，并将其分为两组。第 I 组儿童无龋齿，第 II 组儿童有 ECC。我们测量了从唾液和牙菌斑中收集的 SM 和 IgA 水平。
我们观察到两组之间 SM 水平存在显著差异（<0.001）。唾液总 IgA 与牙菌斑中收集的 SM 之间存在边缘相关性（=0.33，=0.077）。然而，唾液总 IgA 与唾液 SM 之间未检测到显著相关性（=0.35）。
本研究表明唾液免疫系统标志物与 ECC 的发展之间不存在显著关系。
早期儿童龋是一个全球性的公共口腔健康问题，影响着全世界的学龄前儿童。预防它必须成为医疗和牙科界所有专业人员的优先事项。本研究强调了从唾液中收集的总 IgA 和 SM 之间不存在相关性。这并不能完全排除唾液免疫成分的预防作用，但需要进一步研究以更好地理解这种关系。
