Saiful Bahri Athirah, Tuan Mahmood Tuan Mazlelaa, Abdul-Aziz Siti Azdiah, Makmor-Bakry Mohd, Mohamed Shah Noraida
Centre of Quality Management of Medicines, Faculty of Pharmacy, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.
Patient Prefer Adherence. 2021 Feb 3;15:227-235. doi: 10.2147/PPA.S293029. eCollection 2021.
Globally, breast cancer is the most common cancer affecting women, and adjuvant endocrine therapy (AET) is part of its treatment modality, which improves patients' outcome. However, there are concerns on side effects related to its use, which may affect treatment adherence.
This study was conducted to explore attitude and practice on using AET among breast cancer patients in Malaysia.
Postmenopausal breast cancer patients on at least 3 months of AET attending the outpatient oncology clinic at a tertiary care hospital were interviewed. Patients underwent in-depth interviews exploring their attitude and practices while on AET using a semi-structured interview guide. The interviews were transcribed verbatim and analyzed using thematic analysis.
There were four main themes for attitude toward the use of AET: 1) benefits of using AET, 2) concerns on taking AET, 3) beliefs on alternative treatment, and 4) beliefs toward the doctor. For practice, six themes were obtained: 1) correct use of AET, 2) appointment adherence, 3) information-seeking behavior, 4) counseling services obtained, 5) experienced side effects of AET, and 6) usage of complementary and alternative medicines.
Several themes concerning attitude and practice of breast cancer patients receiving AET were identified, which may be addressed during treatment consultations in clinical practice.
在全球范围内，乳腺癌是影响女性的最常见癌症，辅助内分泌治疗（AET）是其治疗方式的一部分，可改善患者的治疗效果。然而，人们担心其使用带来的副作用，这可能会影响治疗依从性。
本研究旨在探讨马来西亚乳腺癌患者对使用AET的态度和行为。
对在一家三级护理医院门诊肿瘤诊所接受至少3个月AET治疗的绝经后乳腺癌患者进行访谈。患者使用半结构化访谈指南接受深入访谈，探讨他们在接受AET治疗时的态度和行为。访谈内容逐字记录，并采用主题分析法进行分析。
对使用AET的态度有四个主要主题：1）使用AET的益处，2）对接受AET的担忧，3）对替代治疗的看法，4）对医生的看法。在行为方面，得到了六个主题：1）正确使用AET，2）遵守预约，3）信息寻求行为，4）获得的咨询服务，5）经历的AET副作用，6）补充和替代药物的使用。
确定了几个关于接受AET的乳腺癌患者态度和行为的主题，在临床实践的治疗咨询中可能需要解决这些问题。
