Wu Kexin, Xiong Zhencheng, Ding Yasuo
Postgraduate School, Dalian Medical University, Dalian, People's Republic of China.
Department of Neurosurgery, Taizhou People's Hospital, Taizhou, People's Republic of China.
Risk Manag Healthc Policy. 2021 Feb 3;14:405-413. doi: 10.2147/RMHP.S285316. eCollection 2021.
Thrombectomy is superior to intravenous thrombolysis for patients with large vessel occlusion in acute ischemic stroke, but nearly half of the patients still experience poor functional outcomes. Elevated blood pressure (BP) is widely observed in acute ischemic stroke, and BP may be one of the modifiable parameters that can potentially influence the outcomes; however, only observational studies exist to support current guidelines, and the recommended range for BP after thrombectomy is too wide to meet the clinical requirement. Randomized controlled trials are therefore needed to better understand the relationship between BP and outcomes after thrombectomy. In this review, we introduce the current management of BP after thrombectomy and several aspects of postthrombectomy BP management that should be resolved in future clinical trials.
对于急性缺血性卒中伴有大血管闭塞的患者,血栓切除术优于静脉溶栓治疗,但仍有近一半的患者功能预后较差。急性缺血性卒中患者普遍存在血压升高的情况,血压可能是一个可调节的参数,有可能影响预后;然而,目前仅有观察性研究支持现行指南,且血栓切除术后血压的推荐范围过宽,无法满足临床需求。因此,需要进行随机对照试验,以更好地了解血压与血栓切除术后预后之间的关系。在本综述中,我们介绍了血栓切除术后血压的当前管理方法以及血栓切除术后血压管理在未来临床试验中应解决的几个方面。