Department of Pediatrics, Korea University College of Medicine, Seoul, Korea.
Asian Pac J Allergy Immunol. 2011 Jun;29(2):143-9.
The importance in asthma management of monitoring of peak expiratory flow rate (PEFR) has been emphasized.
For effective asthma management in Korean children, we established reference ranges for the PEFR in children 4-18 years of age.
The Mini Wright Peak Flow Meter (MWPFM) and spirometry were used in this study. All tests were conducted using a standardized method recommended by the American Thoracic Society.
From a total sample of 2389 children, 826 (34.5%) were excluded based on our exclusion criteria. For both sexes, the PEFR increased with height, age, weight, sitting height and body surface area (BSA). Height and BSA were found to be better predictors of PEFR than the other parameters. The correlation coefficient between FEV1 and PEFR using the MWPFM was 0.886 (p < .001). The reference values of PEFR for height in our study were higher for both sexes than for those previously reported in Korea (p < .005). When we compared our results with those from other countries, the values for boys of the same height were lower than those for European children, but higher than those for African and Turkish children (p < .001).
We have established reference values for PEFR obtained by MWPFM in Korean children in Seoul, and have provided the percentile curves for PEFR as a function of height asthma to assist clinical practices in treating children with asthma in Korea.
监测呼气峰值流速(PEFR)在哮喘管理中的重要性已得到强调。
为了在韩国儿童中进行有效的哮喘管理,我们为 4-18 岁儿童建立了 PEFR 的参考范围。
本研究使用了 Mini Wright 峰值流量计(MWPFM)和肺活量计。所有测试均采用美国胸科学会推荐的标准化方法进行。
在总共 2389 名儿童中,根据我们的排除标准,有 826 名(34.5%)被排除在外。对于男女儿童,PEFR 随身高、年龄、体重、坐高和体表面积(BSA)而增加。身高和 BSA 被发现比其他参数更能预测 PEFR。使用 MWPFM 时,FEV1 和 PEFR 之间的相关系数为 0.886(p<0.001)。我们的研究中 PEFR 与身高的参考值在男女两性均高于韩国以前的报告值(p<0.005)。当我们将结果与其他国家进行比较时,相同身高的男孩值低于欧洲儿童,但高于非洲和土耳其儿童(p<0.001)。
我们在首尔的韩国儿童中建立了通过 MWPFM 获得的 PEFR 参考值,并提供了作为身高哮喘函数的 PEFR 百分位数曲线,以帮助韩国治疗哮喘儿童的临床实践。