Department of Radiation Safety and Security, Paul Scherrer Institute, Switzerland.
Center for Proton Therapy, Paul Scherrer Institute, Switzerland.
Phys Med Biol. 2021 Apr 15;66(8). doi: 10.1088/1361-6560/abe554.
The response of AlO:C optically stimulated luminescence detectors (OSLDs) was investigated in a 250 MeV pencil proton beam. The OSLD response was mapped for a wide range of average dose rates up to 9000 Gy s, corresponding to a ∼150 kGy sinstantaneous dose rate in each pulse. Two setups for ultra-high dose rate (FLASH) experiments are presented, which enable OSLDs or biological samples to be irradiated in either water-filled vials or cylinders. The OSLDs were found to be dose rate independent for all dose rates, with an average deviation <1% relative to the nominal dose for average dose rates of (1-1000) Gy swhen irradiated in the two setups. A third setup for irradiations in a 9000 Gy spencil beam is presented, where OSLDs are distributed in a 3 × 4 grid. Calculations of the signal averaging of the beam over the OSLDs were in agreement with the measured response at 9000 Gy s. Furthermore, a new method was presented to extract the beam spot size of narrow pencil beams, which is in agreement within a standard deviation with results derived from radiochromic films. The AlO:C OSLDs were found applicable to support radiobiological experiments in proton beams at ultra-high dose rates.
采用 250 MeV 笔形质子束研究了 AlO:C 光激励发光探测器(OSLD)的响应。在高达 9000 Gy s 的宽平均剂量率范围内对 OSLD 响应进行了映射,这对应于每个脉冲中约 150 kGy 的瞬时剂量率。提出了两种用于超高剂量率(FLASH)实验的设置,这使得 OSLD 或生物样品可以在充满水的小瓶或圆柱体内被辐照。对于在两种设置中辐照的所有剂量率,发现 OSLD 剂量率独立,平均偏差相对于名义剂量 <1%,当平均剂量率为(1-1000)Gy s 时。提出了一种用于在 9000 Gy s 笔形束中辐照的第三种设置,其中 OSLD 分布在 3×4 网格中。对 OSLD 上光束信号的平均计算与在 9000 Gy s 时测量的响应一致。此外,提出了一种新的方法来提取窄笔形束的束斑大小,该方法与放射性色迹胶片得出的结果在标准偏差内一致。AlO:C OSLD 适用于支持质子束中的超高剂量率放射生物学实验。