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AlO:C 光学激发发光剂量计(OSLDs)用于超高剂量率质子剂量测量。

AlO:C optically stimulated luminescence dosimeters (OSLDs) for ultra-high dose rate proton dosimetry.

机构信息

Department of Radiation Safety and Security, Paul Scherrer Institute, Switzerland.

Center for Proton Therapy, Paul Scherrer Institute, Switzerland.

出版信息

Phys Med Biol. 2021 Apr 15;66(8). doi: 10.1088/1361-6560/abe554.

Abstract

The response of AlO:C optically stimulated luminescence detectors (OSLDs) was investigated in a 250 MeV pencil proton beam. The OSLD response was mapped for a wide range of average dose rates up to 9000 Gy s, corresponding to a ∼150 kGy sinstantaneous dose rate in each pulse. Two setups for ultra-high dose rate (FLASH) experiments are presented, which enable OSLDs or biological samples to be irradiated in either water-filled vials or cylinders. The OSLDs were found to be dose rate independent for all dose rates, with an average deviation <1% relative to the nominal dose for average dose rates of (1-1000) Gy swhen irradiated in the two setups. A third setup for irradiations in a 9000 Gy spencil beam is presented, where OSLDs are distributed in a 3 × 4 grid. Calculations of the signal averaging of the beam over the OSLDs were in agreement with the measured response at 9000 Gy s. Furthermore, a new method was presented to extract the beam spot size of narrow pencil beams, which is in agreement within a standard deviation with results derived from radiochromic films. The AlO:C OSLDs were found applicable to support radiobiological experiments in proton beams at ultra-high dose rates.

摘要

采用 250 MeV 笔形质子束研究了 AlO:C 光激励发光探测器(OSLD)的响应。在高达 9000 Gy s 的宽平均剂量率范围内对 OSLD 响应进行了映射,这对应于每个脉冲中约 150 kGy 的瞬时剂量率。提出了两种用于超高剂量率(FLASH)实验的设置,这使得 OSLD 或生物样品可以在充满水的小瓶或圆柱体内被辐照。对于在两种设置中辐照的所有剂量率,发现 OSLD 剂量率独立,平均偏差相对于名义剂量 <1%,当平均剂量率为(1-1000)Gy s 时。提出了一种用于在 9000 Gy s 笔形束中辐照的第三种设置,其中 OSLD 分布在 3×4 网格中。对 OSLD 上光束信号的平均计算与在 9000 Gy s 时测量的响应一致。此外,提出了一种新的方法来提取窄笔形束的束斑大小,该方法与放射性色迹胶片得出的结果在标准偏差内一致。AlO:C OSLD 适用于支持质子束中的超高剂量率放射生物学实验。

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