Department of Pharmacognosy, Faculty of Pharmacy, Umm Al-Qura University, Makkah 21955, Saudi Arabia.
King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences, Riyadh 11481, Saudi Arabia.
Molecules. 2021 Feb 9;26(4):905. doi: 10.3390/molecules26040905.
In developing countries, crop deterioration is mainly caused by inappropriate storage conditions that promote insect infestation. Synthetic pesticides are associated with serious adverse effects on humans and the environment. Thus, finding alternative "green" insecticides is a very pressing need. (Aiton) Dryand (Apocynaceae) growing in Saudi Arabia was selected for this purpose. LC-MS/MS analysis was applied to investigate the metabolic composition of different extracts. Particularly, latex and leaves showed a high presence of cardenolides including calactin, uscharidin, 15β-hydroxy-calactin, 16β-hydroxy-calactin, and 12β-hydroxy-calactin. The ovicidal activity of the extracts from different plant organs (flowers, leaves, branches, roots), and of the latex, against (Walker) (Lepidoptera, Pyralidae) was assessed. Extracts of roots displayed the most potent activity with 50% of eggs not hatching at 10.000 ppm (1%).
在发展中国家,作物退化主要是由于储存条件不当导致昆虫滋生造成的。合成杀虫剂会对人类和环境造成严重的不良影响。因此,寻找替代的“绿色”杀虫剂是非常紧迫的需求。为此,选择了在沙特阿拉伯生长的(Aiton) Dryand(夹竹桃科)。应用 LC-MS/MS 分析来研究不同提取物的代谢成分。特别是乳胶和叶子含有较高的强心甾内酯,包括卡他林、乌沙里定、15β-羟基卡他林、16β-羟基卡他林和 12β-羟基卡他林。评估了来自不同植物器官(花、叶、枝、根)和乳胶的提取物对(Walker)(鳞翅目,螟蛾科)的杀卵活性。根提取物显示出最强的活性,在 10.000 ppm(1%)时,有 50%的卵未孵化。