Center for Studies and Research of Medicinal Plants, Federal University of San Francisco Valley, 56.304-205, Petrolina-PE, Brazil.
Chemical Research Group of Amazon Micromolecules, Federal University of Amazonas, 69.077-000, Manaus-AM, Brazil.
Chem Biol Interact. 2020 Feb 25;318:108976. doi: 10.1016/j.cbi.2020.108976. Epub 2020 Feb 6.
The genus Jatropha belongs to the Euphorbiaceae family and has about 175 species. Originally from tropical America, the Jatropha genus can be found all over the tropics and subtropics of Asia and Africa. Jatropha species are recognized to be important sources of secondary metabolites with a broad spectrum of biological functions. Extracts and isolated compounds from species of this genus have been known to have properties of cytotoxicity, antimicrobial, antifungal, anti-inflammatory, antioxidant, insecticidal, larvicidal, inhibition AChE, and toxicity activities. Investigations on the chemical aspects of the genus Jatropha have led to the identification of cyclic peptides, lignans, flavonoids, coumarins, alkaloids, eudesmenoic acids, and mainly terpenes. In this review, we provide a comprehensive picture of the phytochemical and biological characteristics of Jatropha species. The information gathered and approached in this paper might support the planning and discussion of future studies on the topic.
麻疯树属属于大戟科，约有 175 种。该属原产于热带美洲，遍布于亚洲和非洲的热带和亚热带地区。麻疯树物种被认为是具有广泛生物功能的次生代谢物的重要来源。该属植物的提取物和分离化合物已被证明具有细胞毒性、抗菌、抗真菌、抗炎、抗氧化、杀虫、杀幼虫、抑制乙酰胆碱酯酶和毒性活性。对麻疯树属的化学方面的研究导致了环肽、木脂素、类黄酮、香豆素、生物碱、桉烷酸和主要萜类化合物的鉴定。在这篇综述中，我们提供了麻疯树属植物的化学和生物学特性的全面描述。本文收集和探讨的信息可能支持对该主题未来研究的规划和讨论。
