Siltrakool Budh, Berrou Ilhem, Griffiths David, Alghamdi Saleh
Department of Clinical, Pharmaceutical and Biological Sciences, School of Life and Medical Sciences, University of Hertfordshire, Hatfield AL10 9AB, UK.
Faculty of Health & Applied Sciences, University of the West of England, Bristol BS16 1DD, UK.
Antibiotics (Basel). 2021 Jan 31;10(2):137. doi: 10.3390/antibiotics10020137.
Thailand spends $203 million on antibiotics every year, and patients can still access antimicrobials over the counter without a prescription. Community pharmacy plays a pivotal role in improving access and ensuring the appropriate use of antimicrobials. However, little is known about current practices in this setting. This study aims to assess Thai community pharmacists' knowledge, attitudes and practices (KAP) regarding antimicrobials' use and resistance. A cross-sectional study was conducted in Bangkok and Chonburi province in 2017 using an online self-administered questionnaire. The questionnaire was completed by 372 community pharmacists (71.4% response rate). The most commonly encountered infections in the community were upper and lower respiratory tract infections. The most commonly dispensed antimicrobials were broad-spectrum antibiotics including aminopenicillins and fluoroquinolones. Thai pharmacists have a good knowledge, attitude, and practice regarding antimicrobials' use and resistance. They dispense anti-microbials in line with local guidelines, although international guidelines may not indicate anti-biotics for viral self-limiting infections. While community pharmacy in Thailand could be the most accessible healthcare resource for patients, inappropriate provision of antimicrobials for self-limiting viral infections by pharmacists will increase antimicrobial resistance. This highlights the need for updated guidance and improved pharmacists' training.
泰国每年在抗生素上花费2.03亿美元，而且患者仍可在无处方的情况下在柜台买到抗菌药物。社区药房在改善抗菌药物的可及性及确保其合理使用方面发挥着关键作用。然而，对于这种情况下的现行做法却知之甚少。本研究旨在评估泰国社区药剂师关于抗菌药物使用及耐药性的知识、态度和做法（KAP）。2017年在曼谷和春武里府开展了一项横断面研究，采用在线自填问卷的方式。372名社区药剂师完成了问卷（应答率为71.4%）。社区中最常遇到的感染是上、下呼吸道感染。最常配发的抗菌药物是包括氨基青霉素和氟喹诺酮在内的广谱抗生素。泰国药剂师在抗菌药物的使用及耐药性方面具备良好的知识、态度和做法。他们按照当地指南配发抗菌药物，尽管国际指南可能并未指明针对病毒自限性感染使用抗生素。虽然泰国的社区药房可能是患者最容易获得的医疗资源，但药剂师为病毒自限性感染不当提供抗菌药物会增加抗菌药物耐药性。这凸显了更新指南及加强药剂师培训的必要性。
