Donsamak Sisira, Weiss Marjorie C, John Dai N
School of Pharmacy and Pharmaceutical Sciences, Cardiff University, Cardiff CF10 3NB, UK.
Faculty of Pharmaceutical Sciences, Ubon Ratchathani University, Warin Chamrab, Ubon Ratchathani 34190, Thailand.
Antibiotics (Basel). 2021 Feb 3;10(2):154. doi: 10.3390/antibiotics10020154.
In Thailand, antibiotics are available lawfully from community pharmacies without a prescription. Inappropriate supply of antibiotics from Thai community pharmacies to the public for common, self-limiting diseases has been reported. The study aimed to evaluate the appropriateness of antibiotics selected by community pharmacists in Thailand in response to vignettes. A cross-sectional survey of community pharmacists across Thailand was conducted using a self-administered questionnaire including nine case vignettes with three conditions, namely upper respiratory infections (URIs), acute diarrhoea and simple wounds. A total of 208 questionnaires were completed and analysed (20.8% response rate). In response to vignettes relating to URIs, 50.8% of pharmacist recommendations were not in accordance with antibiotic guidelines. Inappropriate recommendations for diarrhoea and wound cases were 20.8% and 16.7%, respectively. A higher proportion of younger pharmacists, those with less experience, Pharm. D. graduate pharmacists, employee pharmacists and those pharmacists who worked in a chain pharmacy were more likely to recommend appropriate antibiotic treatment in response to the vignettes ( < 0.05). These findings will be useful to promote educational interventions for community pharmacists regarding common infectious disease management in order to improve appropriate antibiotic use.
在泰国,抗生素无需处方即可从社区药店合法购得。据报道,泰国社区药店向公众不当供应用于常见自限性疾病的抗生素。该研究旨在评估泰国社区药剂师针对病例描述所选择抗生素的合理性。通过一份自填式问卷对泰国各地的社区药剂师进行了横断面调查,问卷包含九个病例描述,涉及三种病症,即上呼吸道感染(URIs)、急性腹泻和简单伤口。共完成并分析了208份问卷(回复率为20.8%)。针对与上呼吸道感染相关的病例描述,50.8%的药剂师建议不符合抗生素使用指南。腹泻和伤口病例的不当建议分别为20.8%和16.7%。年轻药剂师、经验较少的药剂师、药学博士毕业的药剂师、受雇药剂师以及在连锁药店工作的药剂师中,有较高比例的人更有可能针对病例描述推荐适当的抗生素治疗(<0.05)。这些研究结果将有助于推动针对社区药剂师开展常见传染病管理方面的教育干预措施,以促进抗生素的合理使用。