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COVID-19:对新型冠状病毒疾病的进化、传播、检测、控制和预防的综述。

COVID-19: A Review on the Novel Coronavirus Disease Evolution, Transmission, Detection, Control and Prevention.

机构信息

School of Science, Monash University Malaysia, Bandar Sunway 47500, Selangor DE, Malaysia.

Tropical Medicine & Biology Multidisciplinary Platform, Monash University Malaysia, Bandar Sunway 47500, Selangor DE, Malaysia.

出版信息

Viruses. 2021 Jan 29;13(2):202. doi: 10.3390/v13020202.

Abstract

Three major outbreaks of the coronavirus, a zoonotic virus known to cause respiratory disease, have been reported since 2002, including SARS-CoV, MERS-CoV and the most recent 2019-nCoV, or more recently known as SARS-CoV-2. Bats are known to be the primary animal reservoir for coronaviruses. However, in the past few decades, the virus has been able to mutate and adapt to infect humans, resulting in an animal-to-human species barrier jump. The emergence of a novel coronavirus poses a serious global public health threat and possibly carries the potential of causing a major pandemic outbreak in the naïve human population. The recent outbreak of COVID-19, the disease caused by SARS-CoV-2, in Wuhan, Hubei Province, China has infected over 36.5 million individuals and claimed over one million lives worldwide, as of 8 October 2020. The novel virus is rapidly spreading across China and has been transmitted to 213 other countries/territories across the globe. Researchers have reported that the virus is constantly evolving and spreading through asymptomatic carriers, further suggesting a high global health threat. To this end, current up-to-date information on the coronavirus evolution and SARS-CoV-2 modes of transmission, detection techniques and current control and prevention strategies are summarized in this review.

摘要

自 2002 年以来,已经报告了三种主要的冠状病毒爆发,这是一种已知会导致呼吸道疾病的人畜共患病病毒,包括 SARS-CoV、MERS-CoV 和最近的 2019-nCoV,或最近称为 SARS-CoV-2。蝙蝠被认为是冠状病毒的主要动物宿主。然而,在过去几十年中,该病毒能够发生突变并适应感染人类,导致动物到人类的物种屏障突破。新型冠状病毒的出现对全球公共卫生构成了严重威胁,并且有可能导致人类群体中发生重大的大流行爆发。截至 2020 年 10 月 8 日,在中国湖北省武汉市爆发的由 SARS-CoV-2 引起的 COVID-19 疫情已感染超过 3650 万人,并在全球范围内夺走了超过 100 万人的生命。这种新型病毒正在迅速在中国传播,并已传播到全球 213 个其他国家/地区。研究人员报告称,该病毒不断进化并通过无症状携带者传播,这进一步表明了对全球健康的高度威胁。为此,本综述总结了有关冠状病毒进化和 SARS-CoV-2 传播模式、检测技术以及当前控制和预防策略的最新信息。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e495/7911532/365a4d7da29e/viruses-13-00202-g001.jpg

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