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德国唇裂伴/不伴腭裂人群中先天性缺牙和额外牙的患病率。

Prevalence of hypodontia and supernumerary teeth in a German cleft lip with/without palate population.

机构信息

Department of Orthodontics, Carl Gustav Carus Campus TU Dresden, Fetscherstrasse 74, Haus 28, 01307, Dresden, Germany.

Department of Oral and Maxillofacial Surgery, Dresden University Hospital, Fetscherstrasse 74, 01307, Dresden, Germany.

出版信息

BMC Oral Health. 2021 Feb 11;21(1):60. doi: 10.1186/s12903-021-01420-7.

DOI:10.1186/s12903-021-01420-7
PMID:33573652
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7879655/
Abstract

BACKGROUND

The distribution of dental abnormalities among cleft patients concerning cleft type frequently poses ambiguity wherefore the aim of this study was to evaluate the prevalence of hypodontia and supernumerary teeth in an exemplary German cleft population dependent on the cleft type.

METHODS

Radiographs and dental records of cleft patients, which had been treated and followed up in the Department of Oral and Maxillofacial Surgery, University Hospital Carl Gustav Carus Campus, Dresden, Germany (investigation period of 22 years) were evaluated concerning hypodontia and supernumerary teeth dependent on the cleft type. Out of 386 records, 108 patients met the inclusion criteria: non-syndromic cleft of the alveolus with or without palate (CL/P), at least one clear panoramic x-ray, sufficient dental records. Statistical analysis was performed using x-square and binominal test (p ≤ 0.05).

RESULTS

Hypodontia was more frequent (54/50%) than supernumerary teeth (36/33.3%) and was more common in bilateral clefts of the lip and palate (BCLP) (70.1%) than in unilateral clefts of the lip and palate (UCLP) (51.6%) or clefts of the lip and alveolus (CLA) (34.5%) (p << 0.001). There was an average of 0.9 missing teeth per patient, thereof the upper lateral incisor was most often affected (23.2%). In contrast, supernumerary teeth were more frequent in CLA (51.7%; p = 0.014) than UCLP (29.0%) and BCLP patients (17.6%).

CONCLUSION

The prevalence for numerical dental anomalies was significantly different among the cleft types. Hypodontia significantly increased with the extend of the cleft, whereas the prevalence of supernumerary teeth decreased.

摘要

背景

唇腭裂患者的牙齿异常分布与唇腭裂类型常存在混淆,因此本研究旨在评估德国典型唇腭裂人群中,根据唇腭裂类型,缺牙和多生牙的发生率。

方法

评估德国德累斯顿卡尔古斯塔夫卡鲁斯大学医院口腔颌面外科治疗和随访的唇腭裂患者的 X 光片和牙科记录,研究期间为 22 年,根据唇腭裂类型评估缺牙和多生牙。在 386 份记录中,有 108 名患者符合纳入标准:非综合征性牙槽裂伴或不伴腭裂(CL/P),至少有一张清晰的全景 X 光片,有足够的牙科记录。使用卡方检验和二项式检验(p≤0.05)进行统计分析。

结果

缺牙(54/50%)比多生牙(36/33.3%)更常见,双侧唇腭裂(BCLP)(70.1%)比单侧唇腭裂(UCLP)(51.6%)或唇腭裂(CLA)(34.5%)更常见(p<<0.001)。每位患者平均缺牙 0.9 颗,其中上颌侧切牙最常受累(23.2%)。相比之下,CLA 患者(51.7%;p=0.014)的多生牙发生率高于 UCLP(29.0%)和 BCLP 患者(17.6%)。

结论

不同唇腭裂类型的牙齿数目异常发生率存在显著差异。缺牙发生率随唇腭裂程度的增加而显著增加,而多生牙的发生率则降低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0380/7879655/5685217fb870/12903_2021_1420_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0380/7879655/5685217fb870/12903_2021_1420_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0380/7879655/5685217fb870/12903_2021_1420_Fig1_HTML.jpg

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J Stomatol Oral Maxillofac Surg. 2021 Feb;122(1):13-17. doi: 10.1016/j.jormas.2020.07.010. Epub 2020 Aug 15.
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Tooth agenesis and orofacial clefting: genetic brothers in arms?牙齿发育不全与口腔颌面部裂隙:并肩作战的遗传“兄弟”?
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A Longitudinal Study of the Presence of Dental Anomalies in the Primary and Permanent Dentitions of Cleft Lip and/or Palate Patients.
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