Hernández-Flores Julissa-Brillit, Santos-Jaimes Edmundo, Gaitán-Cepeda Luis-Alberto
Second year resident of Oral pathology program, Graduate and Research Division, Dental School, National Autonomous University of Mexico. Mexico city, Mexico.
Professor of Department of Oral Pathology and Oral Medicine, Graduate and Research Division, Dental School, National Autonomous University of Mexico. Mexico city, Mexico.
J Clin Exp Dent. 2021 Feb 1;13(2):e211-e214. doi: 10.4317/jced.57341. eCollection 2021 Feb.
Necrotizing Sialometaplasia (NS) is a rare, benign, self-limited, inflammatory and necrotizing reaction of the salivary glandular tissue. Due to the clinical picture (a painful ulcer with well-defined edges), and histopathological characteristics (nuclear and cellular pleomorphism of ductal cells) NS can mimic a malignant lesion. The correct diagnosis is important because NS shows a spontaneous resolution and therefore no further treatment is needed. We report a very unusual case of spontaneous and recurrent NS located on the anterior tonsillar pillar in a 43-year old man, which clinically mimics a malignant lesion. The clinician should be aware to include NS in the differential diagnosis of ulcers in soft palate and tonsillar pillars. Minor salivary gland, necrotizing sialometaplasia, oral ulcer, squamous cell carcinoma, tonsillar pillar.
坏死性涎腺化生(NS)是一种罕见的、良性的、自限性的涎腺组织炎症性坏死反应。由于临床表现(边缘清晰的疼痛性溃疡)以及组织病理学特征(导管细胞核及细胞多形性),NS可酷似恶性病变。正确诊断很重要,因为NS可自行消退,因此无需进一步治疗。我们报告一例非常罕见的病例,一名43岁男性的扁桃体前柱出现自发性复发性NS,临床上酷似恶性病变。临床医生应注意将NS纳入软腭和扁桃体柱溃疡的鉴别诊断中。小涎腺、坏死性涎腺化生、口腔溃疡、鳞状细胞癌、扁桃体柱