急性风湿热：重要皮肤及组织学表现综述

Heard Matthew A, Green Margaret C, Royer Michael

College of Osteopathic Medicine, University of New England, Biddeford, USA.

Dermatology, Walter Reed National Military Medical Center, Bethesda, USA.

Cureus. 2021 Jan 8;13(1):e12577. doi: 10.7759/cureus.12577.

Acute rheumatic fever (ARF) is an autoimmune response that may occur after infection with group A . Clinical manifestations are protean, making the syndrome difficult to recognize in the 21st century. Secondary prophylaxis with benzathine penicillin is given for 10 years after an episode of ARF to prevent recurrence and reduce the risk of rheumatic heart disease. This case highlights the importance of providing a detailed clinical history to the dermatopathologist when considering ARF in the differential diagnosis.

急性风湿热（ARF）是一种可能在感染A组链球菌后发生的自身免疫反应。其临床表现多样，使得在21世纪该综合征难以识别。ARF发作后，用苄星青霉素进行二级预防10年，以防止复发并降低风湿性心脏病的风险。该病例强调了在鉴别诊断中考虑ARF时，向皮肤病理学家提供详细临床病史的重要性。