Pirelli Luigi, Hong Estee, Steffen Robert, Vahl Torsten P, Kodali Susheel K, Bapat Vinayak
Department of Cardiothoracic Surgery, Northwell Health, Lenox Hill Hospital, New York, NY, USA.
Department of Cardiothoracic Surgery, Columbia University Irvine Medical Center, New York, NY, USA.
Ann Cardiothorac Surg. 2021 Jan;10(1):96-112. doi: 10.21037/acs-2019-mv-169.
Transcatheter aortic valve implantation is now a mainstay of treatment in patients with aortic stenosis who are considered intermediate, high and prohibitive risk for surgery. Extended use of this innovative platform in treating other conditions has led to its approval in treating degenerated aortic bioprosthesis. Similarly, use of transcatheter devices in treating degenerated mitral bioprosthesis and failed mitral valve repairs with annuloplasty rings has opened a potential alternative to surgery in these patients. Experience in mitral valve-in-valve (MVIV) and valve-in-ring (VIR), while still limited, is on the rise. Although similar in many ways to the aortic VIV, it is different with respect to patient selection, planning and procedural steps. Familiarity with the bioprosthetic properties and dimensions can help an operator choose an appropriate transcatheter device and deploy it in an ideal position. Due to greater variability in construction and properties, mitral rings have led to poorer results compared to mitral valve-in-valve. Understanding the properties of mitral rings is critical and has been simplified by us in a stepwise manner. We also describe steps in patient preparation and procedure, which should help operators in performing this procedure. Certain unique complications, such as left ventricular outflow tract obstruction and risk of embolization, are discussed with tips to address these issues. Once these steps are followed, the procedure can be performed with minimal risk and good outcome.
经导管主动脉瓣植入术现已成为主动脉瓣狭窄患者治疗的主要手段,这些患者被认为具有中度、高度和手术禁忌风险。在治疗其他病症中扩展使用这一创新平台已使其获批用于治疗退化性主动脉生物假体。同样,使用经导管装置治疗退化性二尖瓣生物假体以及使用瓣环成形术环修复失败的二尖瓣,为这些患者开辟了一种潜在的手术替代方案。二尖瓣瓣中瓣(MVIV)和瓣中瓣环(VIR)的经验虽然仍然有限,但正在增加。尽管在许多方面与主动脉瓣中瓣相似,但在患者选择、规划和手术步骤方面有所不同。熟悉生物假体的特性和尺寸有助于操作人员选择合适的经导管装置并将其部署在理想位置。由于二尖瓣环在结构和特性方面的变异性更大,与二尖瓣瓣中瓣相比,其效果较差。了解二尖瓣环的特性至关重要,我们已逐步将其简化。我们还描述了患者准备和手术步骤,这应有助于操作人员进行此手术。文中讨论了某些独特的并发症,如左心室流出道梗阻和栓塞风险,并给出了解决这些问题的提示。一旦遵循这些步骤,该手术就可以在风险最小的情况下取得良好的效果。