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The gut-liver axis as a target of liver disease management.肠-肝轴作为肝病管理的靶点。
Hepatobiliary Surg Nutr. 2021 Jan;10(1):100-102. doi: 10.21037/hbsn.2020.03.27.
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[Mechanism of gut-microbiota-liver axis in the pathogenesis of intestinal failure-associated liver disease].[肠道菌群-肝脏轴在肠衰竭相关肝病发病机制中的作用机制]
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Liver-draining portal lymph node responds to enteric nematode infection by generating highly parasite-specific follicular T helper and B cell responses.引流肝脏的门静脉淋巴结通过产生高度寄生虫特异性的滤泡辅助性T细胞和B细胞反应来应对肠道线虫感染。
Front Immunol. 2025 Feb 28;16:1483274. doi: 10.3389/fimmu.2025.1483274. eCollection 2025.
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Reasons why treatment of metabolic dysfunction-associated steatotic liver disease may benefit from targeting the gut-liver axis as well.治疗代谢功能障碍相关脂肪性肝病也可能从靶向肠-肝轴中获益的原因。
United European Gastroenterol J. 2024 May;12(4):528-529. doi: 10.1002/ueg2.12558. Epub 2024 Mar 27.
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Brain-gut-liver axis: Chronic psychological stress promotes liver injury and fibrosis gut in rats.脑-肠-肝轴：慢性心理应激促进大鼠肝损伤和纤维化。
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Insight into the gut microbiome dysbiosis in patients with liver failure after extended-hepatectomy.扩大肝切除术后肝衰竭患者肠道微生物群失调的研究
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Antibiotics and probiotics on hepatic venous pressure gradient in cirrhosis: A systematic review and a meta-analysis.抗生素和益生菌对肝硬化肝静脉压力梯度的影响：系统评价和荟萃分析。
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本文引用的文献

1
Targeted Approaches for In Situ Gut Microbiome Manipulation.靶向肠道微生物组原位操作方法。
JPEN J Parenter Enteral Nutr. 2020 May;44(4):581-588. doi: 10.1002/jpen.1779. Epub 2020 Feb 6.
2
Microbiota changes and intestinal microbiota transplantation in liver diseases and cirrhosis.肝脏疾病和肝硬化中的微生物群变化及肠道微生物群移植
J Hepatol. 2020 May;72(5):1003-1027. doi: 10.1016/j.jhep.2020.01.017. Epub 2020 Jan 28.
3
The effect of a Mediterranean diet on metabolic parameters in patients with non-alcoholic fatty liver disease: A systematic review of randomized controlled trials.地中海饮食对非酒精性脂肪肝患者代谢参数的影响：随机对照试验的系统评价。
Clin Nutr ESPEN. 2020 Feb;35:40-46. doi: 10.1016/j.clnesp.2019.10.008. Epub 2019 Nov 15.
4
Gut microbiome in HCC - Mechanisms, diagnosis and therapy.肝癌中的肠道微生物组：机制、诊断与治疗。
J Hepatol. 2020 Feb;72(2):230-238. doi: 10.1016/j.jhep.2019.08.016.
5
Akkermansia muciniphila Prevents Fatty Liver Disease, Decreases Serum Triglycerides, and Maintains Gut Homeostasis.阿克曼氏菌可预防脂肪肝疾病，降低血清甘油三酯，并维持肠道内环境稳定。
Appl Environ Microbiol. 2020 Mar 18;86(7). doi: 10.1128/AEM.03004-19.
6
Gut microbiota in non-alcoholic fatty liver disease and alcohol-related liver disease: Current concepts and perspectives.非酒精性脂肪性肝病和酒精性肝病中的肠道微生物群：当前概念与展望
Hepatol Res. 2020 Apr;50(4):407-418. doi: 10.1111/hepr.13473. Epub 2020 Jan 13.
7
The gut-liver axis in liver disease: Pathophysiological basis for therapy.肝脏疾病中的肠-肝轴：治疗的病理生理学基础。
J Hepatol. 2020 Mar;72(3):558-577. doi: 10.1016/j.jhep.2019.10.003. Epub 2019 Oct 14.
8
Gut and oral microbiota in autoimmune liver disease.自身免疫性肝病中的肠道和口腔微生物群
Fukushima J Med Sci. 2020 Jan 9;65(3):71-75. doi: 10.5387/fms.2019-21. Epub 2019 Sep 27.
9
Microbiota-driven gut vascular barrier disruption is a prerequisite for non-alcoholic steatohepatitis development.肠道微生物群驱动的肠道血管屏障破坏是非酒精性脂肪性肝炎发展的前提。
J Hepatol. 2019 Dec;71(6):1216-1228. doi: 10.1016/j.jhep.2019.08.005. Epub 2019 Aug 13.
10
Next generation probiotics in disease amelioration.改善疾病的新一代益生菌。
J Food Drug Anal. 2019 Jul;27(3):615-622. doi: 10.1016/j.jfda.2018.12.011. Epub 2019 Feb 2.

The gut-liver axis as a target of liver disease management.

作者信息

Mandato Claudia, Delli Bovi Anna Pia, Vajro Pietro

机构信息

Department of Pediatrics, AORN "Santobono-Pausilipon", Naples, Italy.

Pediatrics, Department of Medicine and Surgery University of Salerno, Salerno, Italy.

出版信息

Hepatobiliary Surg Nutr. 2021 Jan;10(1):100-102. doi: 10.21037/hbsn.2020.03.27.

DOI:10.21037/hbsn.2020.03.27
PMID:33575294
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7867728/
Abstract
摘要