Erzincan Binali Yildirim University, Faculty of Medicine, Department of Neurosurgery, Erzincan, Turkey.
Turk Neurosurg. 2021;31(2):199-205. doi: 10.5137/1019-5149.JTN.29765-20.2.
To compare the clinical and radiological results of using synthetic bone graft versus autograft obtained from the spinous process in posterior lumbar interbody fusion.
This retrospective study included 102 patients with degenerative lumbar spondylolisthesis who underwent one-segment posterior lumbar interbody fusion (PLIF) followed by one-segment posterior transpedicular instrumentation. PLIF surgery was performed using a local solid bone graft obtained from the spinous process in group A and using a synthetic solid calcium hydroxyapatite block in group B. The Oswestry Disability Index (ODI), visual analogue scale (VAS) scores, degree of bone formation, intervertebral disc heights at the operation segment, wound infection, and instrumentation complications were compared between the 6-month and 5-year follow-ups.
In both groups, ODI and VAS scores significantly improved at the 6-month and 5-year follow-up. Bone formation at both 6 months and 5 years were higher in group A than that in group B, but without a significant difference when compared. Moreover, the difference in maintaining the intervertebral disc heights was not significant between the two groups. Surgical wound infection more commonly occurred in group B, but without significant difference between the two groups, and rod fractures were observed in two patients in group B; however, no metal breakage was observed in group A.
Successful fusion of the intervertebral space and intervertebral height restoration can be achieved and maintained with an autograft from the patient's spinous processes.
比较后路腰椎体间融合术中使用合成骨移植物与棘突自体骨移植物的临床和影像学结果。
本回顾性研究纳入了 102 例退行性腰椎滑脱症患者,这些患者均接受了单节段后路腰椎体间融合(PLIF)及单节段后路经椎弓根内固定术。A 组患者采用棘突局部固体骨移植物进行 PLIF 手术,B 组患者采用合成固体羟基磷灰石块进行。在 6 个月和 5 年随访时,比较 Oswestry 功能障碍指数(ODI)、视觉模拟评分(VAS)评分、骨形成程度、手术节段椎间盘高度、伤口感染和器械并发症。
两组患者在 6 个月和 5 年随访时 ODI 和 VAS 评分均显著改善。A 组在 6 个月和 5 年时的骨形成均高于 B 组,但差异无统计学意义。此外,两组间椎间盘高度的维持差异无统计学意义。B 组的手术伤口感染更为常见,但两组间无显著差异,B 组有 2 例患者出现内固定棒断裂,但 A 组无金属断裂。
采用患者棘突自体骨移植物可成功融合椎间隙并维持椎间高度。