Division of Dermatology, The University of Ottawa, The Ottawa Hospital, Ottawa, Canada.
Faculty of Medicine, University of Ottawa, Ottawa, Canada.
Dermatol Surg. 2021 Jun 1;47(6):755-761. doi: 10.1097/DSS.0000000000002972.
Many studies have evaluated radiofrequency microneedling (RFMN) in various dermatologic conditions. However, the efficacy and safety of RFMN, and how it compares with other energy-based devices in a clinician's armamentarium, remains unclear.
To review higher-quality evidence supporting RFMN and the dermatologic conditions which it can be used in.
A search was conducted in MEDLINE and EMBASE from inception to May 13, 2020, using the terms: "radiofrequency microneedling" OR "fractional radiofrequency" OR "radiofrequency needling" OR "radiofrequency percutaneous collagen induction." Only randomized, split body or blinded studies with original data on humans were included. Non-English or non-dermatology-related studies were excluded.
Forty-two higher-quality studies were included after applying the inclusion and exclusion criteria. There were 14 studies for skin rejuvenation, 7 for acne scars, 6 for acne vulgaris, 5 each for striae and axillary hyperhidrosis, 2 for melasma, and 1 each for rosacea, cellulite, and androgenetic alopecia.
Radiofrequency microneedling is an effective intervention that can be used repeatedly and safely in combination with other treatment modalities and in individuals with darker skin phototypes. Radiofrequency microneedling-induced dermal remodeling and neocollagenesis are slow and progressive but continue to improve even 6 months after treatment.
许多研究已经评估了射频微针（RFMN）在各种皮肤科疾病中的应用。然而，RFMN 的疗效和安全性，以及它在临床医生的武器库中与其他能量设备相比如何，仍然不清楚。
回顾支持 RFMN 并可用于治疗的皮肤科疾病的更高质量证据。
从 MEDLINE 和 EMBASE 数据库中搜索了从成立到 2020 年 5 月 13 日的所有相关研究，使用的术语为：“射频微针”或“分数射频”或“射频针刺”或“射频经皮胶原诱导”。仅纳入了包含人类原始数据的随机、分体或盲法研究，排除了非英语或非皮肤科相关的研究。
应用纳入和排除标准后，共纳入了 42 项高质量研究。其中 14 项研究用于皮肤年轻化，7 项用于治疗痤疮疤痕，6 项用于治疗寻常痤疮，5 项分别用于治疗妊娠纹和腋窝多汗症，2 项用于治疗黄褐斑，1 项分别用于治疗酒渣鼻、蜂窝织炎和雄激素性脱发。
射频微针是一种有效的干预手段，可与其他治疗方式联合使用，且可安全地重复应用于深色皮肤类型的个体。射频微针诱导的真皮重塑和新胶原形成是缓慢和渐进的，但即使在治疗后 6 个月仍在持续改善。
