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杂交修复与传统开放修复方法治疗主动脉弓部疾病:全面综述。

Hybrid Repair versus Conventional Open Repair Approaches for Aortic Arch Disease: a Comprehensive Review.

机构信息

Department of Integrated Medicine, Onofre Lopes University Hospital, Federal University of Rio Grande do Norte, Natal, Brazil.

Dante Pazzanese Institute of Cardiology, São Paulo, SP, Brazil.

出版信息

Braz J Cardiovasc Surg. 2021 Apr 1;36(2):244-252. doi: 10.21470/1678-9741-2020-0382.

Abstract

OBJECTIVE

To investigate whether hybrid repair has supremacy over conventional open repair in aortic arch diseases.

METHODS

A comprehensive search was undertaken in two major databases (PubMed and MEDLINE) to identify all studies comparing the two surgical techniques in five years, up to December 2018, that met the established criteria in this study. The search returned 310 papers, and 305 were selected after removing duplicates. The abstracts of the remaining articles were assessed, resulting in 15 studies that went to full-text analysis. After application of the inclusion and exclusion criteria, 8 papers remained for the final revision.

RESULTS

Eight studies met the criteria, with the inclusion of 1,837 patients. From a short-term perspective, hybrid repair and conventional open repair had similar outcomes in terms of postoperative mortality and acute neurological events. Hybrid repair was associated with less respiratory complications and risk of new intervention, as well as reduced hospital length of stay. Conventional open repair showed better mid- and long-term outcomes.

CONCLUSION

Hybrid repair should be used in selected patients, with a high risk or very high-risk profile for conventional surgery. Finally, since most of the current data were obtained from limited to large samples, with narrow follow-up and had great heterogeneity, the best approach to the aortic arch is still variable. Therefore, the decision of the approach should be individualized and evaluated by the whole Heart Team, considering the expertise of the surgical team.

摘要

目的

探讨杂交手术修复在主动脉弓部疾病中的应用是否优于传统的开放手术修复。

方法

在两个主要数据库(PubMed 和 MEDLINE)中进行全面检索,以确定在五年内比较两种手术技术的所有研究,检索截止日期为 2018 年 12 月,符合本研究标准。检索返回 310 篇论文,排除重复后选择 305 篇。评估其余文章的摘要,有 15 篇文章进行全文分析。应用纳入和排除标准后,有 8 篇论文符合最终修订标准。

结果

8 项研究符合标准,共纳入 1837 例患者。从短期来看,杂交手术修复和传统开放手术修复在术后死亡率和急性神经事件方面的结果相似。杂交手术修复与较少的呼吸并发症和新干预风险相关,同时住院时间较短。传统开放手术修复显示出更好的中期和长期结果。

结论

应在高风险或极高风险的传统手术患者中选择使用杂交手术修复。最后,由于目前大多数数据来自有限的大样本,随访时间窄且存在很大的异质性,主动脉弓部的最佳处理方法仍然存在差异。因此,处理方法的决策应该个体化,并由整个心脏团队进行评估,考虑到手术团队的专业知识。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9501/8163269/524fb32c93e2/rbccv-36-02-0244-g01.jpg

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