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主动脉弓的杂交和全腔内修复。

Hybrid and total endovascular repair of the aortic arch.

机构信息

Department of Vascular Surgery, Royal Free Hospital, Royal Free London NHS Foundation Trust, London, UK.

Department of Vascular Surgery, St Mary's Hospital, Imperial College Healthcare NHS Trust, London, UK.

出版信息

Br J Surg. 2018 Mar;105(4):315-327. doi: 10.1002/bjs.10713.

Abstract

BACKGROUND

Recent advances in endovascular technology have enabled minimally invasive repair of the aortic arch, with specifically designed stent-grafts. This article reviews hybrid and total endovascular repair in the management of aortic arch pathology.

METHODS

Studies relating to aortic arch management were identified using MEDLINE and Embase, focusing on endovascular repair.

RESULTS

Hybrid arch repair is associated with an early mortality rate of some 12 per cent, and carries significant risk of stroke (up to 15 per cent), paraplegia (up to 6 per cent), retrograde dissection (up to 6·5 per cent) and proximal endoleak (6 per cent). Despite patients being of overall higher perioperative risk, hybrid repair has morbidity and early mortality rates comparable to those of open arch replacement. However, rates of freedom from aortic rupture or reintervention are significantly lower in the longer term, owing to the incidence of endoleak. Total endovascular arch repair may be achieved by the use of parallel stents or in situ fenestration in the emergency setting, or use of custom-made devices (scalloped, fenestrated or branched stent-grafts) in the elective setting. Reports of these relatively novel technologies suggest acceptable short-term outcomes, but long-term data are still awaited.

CONCLUSION

Repair of aortic arch pathology presents a formidable challenge for endovascular technology. Open aortic arch repair remains the standard in younger, fitter patients, but endovascular technology and experience continue to evolve with encouraging early outcomes and expanding indications.

摘要

背景

血管内技术的最新进展使得微创修复主动脉弓成为可能,特别是使用专门设计的支架移植物。本文回顾了主动脉弓病变的杂交和全腔内修复治疗。

方法

使用 MEDLINE 和 Embase 确定与主动脉弓管理相关的研究,重点是腔内修复。

结果

杂交弓修复的早期死亡率约为 12%,并伴有显著的中风风险(高达 15%)、截瘫(高达 6%)、逆行夹层(高达 6.5%)和近端内漏(6%)。尽管患者的围手术期风险总体较高,但杂交修复的发病率和早期死亡率与开放弓置换相当。然而,由于内漏的发生,长期来看,主动脉破裂或再次干预的无复发率明显较低。全腔内弓修复可通过在紧急情况下使用平行支架或原位开窗,或在择期情况下使用定制装置(扇贝形、开窗或分支支架移植物)来实现。这些相对较新的技术的报告表明,短期结果可以接受,但仍需要长期数据。

结论

主动脉弓病变的修复对血管内技术提出了严峻的挑战。在年轻、健康的患者中,开放式主动脉弓修复仍然是标准治疗方法,但血管内技术和经验仍在不断发展,早期结果令人鼓舞,适应证不断扩大。

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