Institute of Advanced Synthesis, School of Chemistry and Molecular Engineering, Nanjing Tech University, Nanjing 211816, China.
Department of Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, China.
Org Lett. 2021 Mar 5;23(5):1611-1615. doi: 10.1021/acs.orglett.1c00043. Epub 2021 Feb 12.
An iron-catalyzed α,β-dehydrogenation of carbonyl compounds was developed. A broad spectrum of carbonyls or analogues, such as aldehyde, ketone, lactone, lactam, amine, and alcohol, could be converted to their α,β-unsaturated counterparts in a simple one-step reaction with high yields.
发展了一种铁催化的羰基化合物的α,β-脱氢反应。醛、酮、内酯、内酰胺、胺和醇等广泛的羰基化合物或类似物可以在简单的一步反应中转化为其α,β-不饱和化合物，产率高。
