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纯氧化铜和锌掺杂氧化铜对病原菌的结构、光学及抗菌效果

Structural, Optical and Antibacterial Efficacy of Pure and Zinc-Doped Copper Oxide against Pathogenic Bacteria.

作者信息

Khalid Awais, Ahmad Pervaiz, Alharthi Abdulrahman I, Muhammad Saleh, Khandaker Mayeen Uddin, Rehman Mubasher, Faruque Mohammad Rashed Iqbal, Din Israf Ud, Alotaibi Mshari A, Alzimami Khalid, Bradley David A

机构信息

Department of Physics, Hazara University Mansehra, Khyber Pakhtunkhwa 21300, Pakistan.

Department of Physics, University of Azad Jammu and Kashmir, Muzaffarabad 13100, Pakistan.

出版信息

Nanomaterials (Basel). 2021 Feb 10;11(2):451. doi: 10.3390/nano11020451.

Abstract

Copper oxide and Zinc (Zn)-doped Copper oxide nanostructures (CuO-NSs) are successfully synthesized by using a hydrothermal technique. The as-obtained pure and Zn-doped CuO-NSs were tested to study the effect of doping in CuO on structural, optical, and antibacterial properties. The band gap of the nanostructures is calculated by using the Tauc plot. Our results have shown that the band gap of CuO reduces with the addition of Zinc. Optimization of processing conditions and concentration of precursors leads to the formation of pine needles and sea urchin-like nanostructures. The antibacterial properties of obtained Zn-doped CuO-NSs are observed against Gram-negative and Gram-positive bacteria via the agar well diffusion method. Zn doped s are found to have more effective bacterial resistance than pure CuO. The improved antibacterial activity is attributed to the reactive oxygen species (ROS) generation.

摘要

采用水热法成功合成了氧化铜和锌(Zn)掺杂的氧化铜纳米结构(CuO-NSs)。对所制备的纯CuO-NSs和Zn掺杂的CuO-NSs进行测试,以研究CuO中掺杂对其结构、光学和抗菌性能的影响。利用Tauc图计算纳米结构的带隙。我们的结果表明,随着锌的加入,CuO的带隙减小。通过优化工艺条件和前驱体浓度,形成了松针状和海胆状纳米结构。通过琼脂孔扩散法观察了所制备的Zn掺杂CuO-NSs对革兰氏阴性菌和革兰氏阳性菌的抗菌性能。发现Zn掺杂的CuO比纯CuO具有更有效的抗菌能力。抗菌活性的提高归因于活性氧(ROS)的产生。

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