Pozzi-Mucelli R S, Cova M A, Gozzi G, Dalla Palma L
Istituto di Radiologia, Università degli Studi, Trieste.
Radiol Med. 1988 Mar;75(3):145-50.
The authors have evaluated bone mineral content in the vertebral spongiosa by means of Computed Tomography. The method proposed by Genant and Cann has been applied to examine 164 healthy volunteers and 108 patients. Both healthy males and females showed a progressive bone mineral loss increasing with age; the bone mineral loss was most severe in females during the 4th and 5th decade of life. Pathology included patients with osteoporotic fractures (vertebral and femoral neck), patients with partial gastrectomy, renal failure, primary hyperparathyroidism, Cushing syndrome, corticosteroid therapy. Bone mineral values were significantly lower in most pathologic groups. Computed Tomography proves thus to be a valuable method to assess bone mineral content and to identify patients at risk for fractures.
作者通过计算机断层扫描评估了椎体松质骨的骨矿物质含量。采用Genant和Cann提出的方法对164名健康志愿者和108名患者进行了检查。健康男性和女性均显示骨矿物质随年龄增长逐渐流失;在40至50岁期间,女性的骨矿物质流失最为严重。病理情况包括骨质疏松性骨折(椎体和股骨颈)患者、部分胃切除术患者、肾衰竭患者、原发性甲状旁腺功能亢进患者、库欣综合征患者、接受皮质类固醇治疗的患者。大多数病理组的骨矿物质值显著较低。因此,计算机断层扫描被证明是评估骨矿物质含量和识别骨折高危患者的一种有价值的方法。