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Ozenoxacin: A novel topical antibiotic.

作者信息

Santhosh Parvathy, Thomas Mithun Harold

机构信息

Department of Dermatology, Malabar Medical College Hospital and Research Centre, Kozhikode, Kerala, India.

Department of Gastroenterology, Government Medical College, Kozhikode, Kerala, India.

出版信息

Indian J Dermatol Venereol Leprol. 2021 Jan-Feb;87(1):131-134. doi: 10.25259/IJDVL_191_20.

DOI:10.25259/IJDVL_191_20
PMID:33580932
Abstract
摘要

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In vitro activity of Ozenoxacin against quinolone-susceptible and quinolone-resistant gram-positive bacteria.奥扎诺星对耐喹诺酮和敏感的革兰阳性菌的体外活性。
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Ozenoxacin: A Novel Drug Discovery for the Treatment of Impetigo.奥泽沙星:一种用于治疗脓疱病的新型药物发现。
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[Pharmacological profiles and clinical effects of ozenoxacin lotion for the treatments of acne vulgaris and superficial infection of the skin].奥泽沙星洗剂治疗寻常痤疮和皮肤浅表感染的药理特性及临床疗效
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QbD Based Formulation Development and Optimisation of Ozenoxacin Topical Nano-Emulgel and Efficacy Evaluation Using Impetigo Mice Model.基于 QbD 的奥青纳米乳剂的制剂开发和优化及在脓疱疮小鼠模型中的疗效评价。
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In vitro selection of mutants resistant to ozenoxacin compared with levofloxacin and ciprofloxacin in Gram-positive cocci.在体外筛选对奥扎诺星耐药的突变体与左氧氟沙星和环丙沙星在革兰阳性球菌。
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本文引用的文献

1
Ozenoxacin, a New Effective and Safe Topical Treatment for Impetigo in Children and Adolescents.奥昔沙星,一种治疗儿童和青少年脓疱疮的有效且安全的新型外用药物。
Dermatology. 2020;236(3):199-207. doi: 10.1159/000504536. Epub 2020 Jan 20.
2
Ozenoxacin: a review of preclinical and clinical efficacy.奥昔沙星:临床前和临床疗效评价。
Expert Rev Anti Infect Ther. 2019 Mar;17(3):159-168. doi: 10.1080/14787210.2019.1573671. Epub 2019 Feb 11.
3
Ozenoxacin: A Novel Topical Quinolone for Impetigo.奥洛昔康:一种用于脓疱疮的新型外用喹诺酮类药物。
Ann Pharmacother. 2018 Dec;52(12):1233-1237. doi: 10.1177/1060028018786510. Epub 2018 Jul 2.
4
Efficacy and Safety of Ozenoxacin Cream for Treatment of Adult and Pediatric Patients With Impetigo: A Randomized Clinical Trial.奥昔康唑乳膏治疗成人和儿童脓疱疮的疗效和安全性:一项随机临床试验。
JAMA Dermatol. 2018 Jul 1;154(7):806-813. doi: 10.1001/jamadermatol.2018.1103.
5
Comparative in vitro antibacterial activity of ozenoxacin against Gram-positive clinical isolates.唑诺沙星对革兰阳性临床分离菌的体外抗菌活性比较。
Future Microbiol. 2018 May 1;13:3-19. doi: 10.2217/fmb-2017-0289.
6
Therapeutic efficacy of ozenoxacin in animal models of dermal infection with Staphylococcus aureus.奥昔沙星治疗金黄色葡萄球菌皮肤感染动物模型的疗效。
Future Microbiol. 2018 May 1;13:21-30. doi: 10.2217/fmb-2017-0290.
7
Studies on articular and general toxicity of orally administered ozenoxacin in juvenile rats and dogs.口服奥扎诺星在幼年大鼠和犬的关节和全身毒性研究。
Future Microbiol. 2018 May 1;13:31-40. doi: 10.2217/fmb-2017-0291.
8
Ozenoxacin: A Novel Drug Discovery for the Treatment of Impetigo.奥泽沙星:一种用于治疗脓疱病的新型药物发现。
Curr Drug Discov Technol. 2019;16(3):259-264. doi: 10.2174/1570163815666180502165014.
9
Activities of gyrase and topoisomerase IV on positively supercoiled DNA.促旋酶和拓扑异构酶IV对正超螺旋DNA的活性。
Nucleic Acids Res. 2017 Sep 19;45(16):9611-9624. doi: 10.1093/nar/gkx649.
10
Fusidic Acid: A Bacterial Elongation Factor Inhibitor for the Oral Treatment of Acute and Chronic Staphylococcal Infections.夫西地酸:一种用于口服治疗急慢性葡萄球菌感染的细菌延伸因子抑制剂。
Cold Spring Harb Perspect Med. 2016 Jan 4;6(1):a025437. doi: 10.1101/cshperspect.a025437.