睡眠和警觉性障碍与物质使用障碍：双向关系。
Sleep and alertness disturbance and substance use disorders: A bi-directional relation.
机构信息
Sleep Medicine, Henry Ford Health System, Detroit, MI, United States of America; Dept of Psychiatry & Behavioral Neuroscience, Wayne State University, SOM, Detroit, MI, United States of America; Dept of Psychology, University of Detroit Mercy, Detroit, MI, United States of America.
Sleep Medicine, Henry Ford Health System, Detroit, MI, United States of America; Dept of Psychology, University of Detroit Mercy, Detroit, MI, United States of America.
出版信息
Pharmacol Biochem Behav. 2021 Apr;203:173153. doi: 10.1016/j.pbb.2021.173153. Epub 2021 Feb 12.
Abstract
The majority of the literature describing the relation of sleep/alertness disturbance and substance use disorders (SUD) has focused on the disruptive effects of substances with abuse liability on sleep and alertness. Rarely have studies or literature reviews assessed or discussed how sleep/alertness disturbance affects substance use. This paper focuses on the sleep/alertness disturbance side of the relation. We argue that the relation is bi-directional and review evidence showing that sleep/alertness disturbance affects all phases of the addiction cycle, including the initiation, maintenance and relapse of SUD. We review a variety of substances across all phases of the addiction cycle and conclude sleep/alertness disturbance is a critical factor in both understanding and treating SUD.
摘要
大多数描述睡眠/觉醒障碍与物质使用障碍（SUD）关系的文献都集中在具有滥用倾向的物质对睡眠和觉醒的干扰作用上。很少有研究或文献综述评估或讨论睡眠/觉醒障碍如何影响物质使用。本文侧重于该关系中睡眠/觉醒障碍的一面。我们认为这种关系是双向的，并回顾了表明睡眠/觉醒障碍影响成瘾周期所有阶段的证据，包括 SUD 的开始、维持和复发。我们回顾了成瘾周期各个阶段的各种物质，并得出结论，睡眠/觉醒障碍是理解和治疗 SUD 的关键因素。
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