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霍乱大流行对身高的长期异质影响:来自日本工业化时期的证据。

The long-run heterogeneous effects of a cholera pandemic on stature: Evidence from industrializing Japan.

机构信息

Department of Industrial Engineering, School of Engineering, Tokyo Institute of Technology, 2-12-1, Ookayama, Meguro-ku, Tokyo 152-8552, Japan.

Department of Business Economics, School of Management, Tokyo University of Science, 1-11-2, Fujimi, Chiyoda-ku, Tokyo 102-0071, Japan.

出版信息

Econ Hum Biol. 2021 May;41:100968. doi: 10.1016/j.ehb.2020.100968. Epub 2021 Feb 6.

DOI:10.1016/j.ehb.2020.100968
PMID:33582501
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9760307/
Abstract

The recent COVID-19 pandemic poses the general question on how infectious diseases can persistently affect human health. A growing body of literature has found a significant amount of evidence on the long-term adverse effects of infectious diseases, such as influenza, typhoid fever, and yellow fever. However, we must be careful about the fact that little is known about the long-term consequences of the acute diarrheal disease pandemic cholera - Vibrio cholerae bacillus - which still threatens the health of the population in many developing countries. To bridge this gap in the body of knowledge, we utilized unique census-based data on army height at age 20 in early 20th-century Japan, with a difference-in-differences estimation strategy using regional variation in the intensity of cholera pandemics. We found that early-life exposure to a cholera pandemic had heterogeneous stunting effects on the final height of men; the magnitude of the stunting effects increased as the intensity of exposure increased.

摘要

最近的 COVID-19 大流行提出了一个普遍的问题,即传染病如何持续影响人类健康。越来越多的文献发现了大量关于传染病(如流感、伤寒和黄热病)的长期不良影响的证据。然而,我们必须小心,因为对于急性腹泻病大流行霍乱——霍乱弧菌——的长期后果知之甚少,这种疾病仍然威胁着许多发展中国家的人口健康。为了弥合这一知识空白,我们利用了 20 世纪初日本军队在 20 岁时身高的独特普查数据,采用了基于差异的差异估计策略,利用了霍乱大流行强度的区域差异。我们发现,生命早期接触霍乱大流行对男性的最终身高有不同的生长迟缓影响;暴露强度越大,生长迟缓的影响程度越大。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe89/9760307/ac26699b1a26/gr11_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe89/9760307/c632add1bc36/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe89/9760307/d60426349055/gr2_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe89/9760307/0a53b3a7a467/gr3_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe89/9760307/8639b843750b/gr4_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe89/9760307/0a1192135e7f/gr5_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe89/9760307/4cef74312259/gr6_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe89/9760307/d0ab1a529f04/gr7_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe89/9760307/689739c280af/gr8_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe89/9760307/979127cdf61f/gr9_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe89/9760307/2a0df0a7e757/gr10_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe89/9760307/ac26699b1a26/gr11_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe89/9760307/c632add1bc36/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe89/9760307/d60426349055/gr2_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe89/9760307/0a53b3a7a467/gr3_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe89/9760307/8639b843750b/gr4_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe89/9760307/0a1192135e7f/gr5_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe89/9760307/4cef74312259/gr6_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe89/9760307/d0ab1a529f04/gr7_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe89/9760307/689739c280af/gr8_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe89/9760307/979127cdf61f/gr9_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe89/9760307/2a0df0a7e757/gr10_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe89/9760307/ac26699b1a26/gr11_lrg.jpg

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