Department of Industrial Engineering, School of Engineering, Tokyo Institute of Technology, 2-12-1, Ookayama, Meguro-ku, Tokyo 152-8552, Japan.
Department of Business Economics, School of Management, Tokyo University of Science, 1-11-2, Fujimi, Chiyoda-ku, Tokyo 102-0071, Japan.
Econ Hum Biol. 2021 May;41:100968. doi: 10.1016/j.ehb.2020.100968. Epub 2021 Feb 6.
The recent COVID-19 pandemic poses the general question on how infectious diseases can persistently affect human health. A growing body of literature has found a significant amount of evidence on the long-term adverse effects of infectious diseases, such as influenza, typhoid fever, and yellow fever. However, we must be careful about the fact that little is known about the long-term consequences of the acute diarrheal disease pandemic cholera - Vibrio cholerae bacillus - which still threatens the health of the population in many developing countries. To bridge this gap in the body of knowledge, we utilized unique census-based data on army height at age 20 in early 20th-century Japan, with a difference-in-differences estimation strategy using regional variation in the intensity of cholera pandemics. We found that early-life exposure to a cholera pandemic had heterogeneous stunting effects on the final height of men; the magnitude of the stunting effects increased as the intensity of exposure increased.
最近的 COVID-19 大流行提出了一个普遍的问题,即传染病如何持续影响人类健康。越来越多的文献发现了大量关于传染病(如流感、伤寒和黄热病)的长期不良影响的证据。然而,我们必须小心,因为对于急性腹泻病大流行霍乱——霍乱弧菌——的长期后果知之甚少,这种疾病仍然威胁着许多发展中国家的人口健康。为了弥合这一知识空白,我们利用了 20 世纪初日本军队在 20 岁时身高的独特普查数据,采用了基于差异的差异估计策略,利用了霍乱大流行强度的区域差异。我们发现,生命早期接触霍乱大流行对男性的最终身高有不同的生长迟缓影响;暴露强度越大,生长迟缓的影响程度越大。